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Sodium deoxycholate

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Sodium deoxycholate Basic information

Product Name:
Sodium deoxycholate
CAS:
302-95-4
MF:
C24H39NaO4
MW:
414.55
EINECS:
206-132-7
Mol File:
302-95-4.mol
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Sodium deoxycholate Chemical Properties

Melting point:
357-365 °C
alpha 
44 º (c=2, H2O)
Flash point:
>110°C (own results)
storage temp. 
Store at RT.
solubility 
water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow
form 
Powder
color 
Yellow-tan
Odor
Odorless
PH
7.5-9.0 (20g/l, H2O, 20℃)
PH Range
7 - 10
optical activity
[α]20/D +44±2°, c = 2% in H2O
Water Solubility 
330 g/L (15 ºC)
BRN 
3581950
CAS DataBase Reference
302-95-4(CAS DataBase Reference)
EPA Substance Registry System
Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3.alpha.,5.beta.,12.alpha.)- (302-95-4)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-37
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
FZ2250000
3-10
TSCA 
Yes
HS Code 
29181930
Toxicity
LD50 orally in Rabbit: 1370 mg/kg

MSDS

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Sodium deoxycholate Usage And Synthesis

Chemical Properties

Sodium deoxycholate is white to cream crystalline powder

Uses

Sodium deoxycholate is used as a component in cell lysis buffers.

Uses

Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins.

Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO.

Purification Methods

Recrystallise it from EtOH and dry it in an oven at 100o. The solution is freed from soluble components by repeated extraction with acid-washed charcoal. [Beilstein 10 IV 1608.]

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