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Itraconazole Structure

Itraconazole

Chemical Properties

Melting point 166°C
Boiling point 850.0±75.0 °C(Predicted)
alpha  -0.1~+0.1°(D/20℃)(c=10,CH2Cl2)
Density  1.27 g/cm3
Flash point >110°(230°F)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear, colorless
pka 3.7(at 25℃)
form  White powder
color  white
Water Solubility  Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck  14,5245
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey VHVPQPYKVGDNFY-UHFFFAOYSA-N
CAS DataBase Reference 84625-61-6(CAS DataBase Reference)

Safety Information

Hazard Codes  Xi,Xn,T,F
Risk Statements  36/37/38-36/38-22-39/23/24/25-23/24/25-11
Safety Statements  22-26-36-45-36/37-16
RIDADR  UN 3286 8(6.1)(3) / PGII
WGK Germany  3
RTECS  XZ5481000
HS Code  2934990002
Hazardous Substances Data 84625-61-6(Hazardous Substances Data)
Toxicity LD50 (14 day) in mice, rats, dogs (mg/kg): >320, >320, >200 orally (Van Cauteren)

Usage And Synthesis

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