Basic information Safety Related Supplier
D-METHAMPHETAMINE Structure

D-METHAMPHETAMINE

Chemical Properties

Melting point 143°C (estimate)
Boiling point 230.33°C (estimate)
Density  0.9285 (estimate)
refractive index  1.5105 (estimate)
Flash point 9℃
storage temp.  2-8°C
pka 10.38±0.10(Predicted)

Safety Information

Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  16-36/37-45
RIDADR  1851
WGK Germany  1
HazardClass  6.1(b)
PackingGroup  III
Hazardous Substances Data 537-46-2(Hazardous Substances Data)
Toxicity A widely abused drug; a sympathomimetic and central stimulant that has been used clinically as an anorectic agent. The use of methamphetamine and related drugs in treating obesity is, however, now generally discredited. It may cause elevation of blood pressure, palpitation, and tachycardia, as well as various CNS effects, including psychotic effects at higher doses. Chronic use of methamphetamine and related compounds, especially at high doses as often occurs with drug abuse, can cause a condition often indistinguishable from schizophrenia. Abrupt withdrawal may cause fatigue, depression, and sleep changes. Methamphetamine is an indirect-acting adrenergic and dopamine agonist that acts principally to release endogenous catecholamines, thereby increasing their synaptic availability. Many of its actions can be blocked by adrenergic and dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg.

Usage And Synthesis

Preparation Products And Raw materials