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4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole

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4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Basic information

Product Name:
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
CAS:
10199-89-0
MF:
C6H2ClN3O3
MW:
199.55
EINECS:
233-496-4
Mol File:
10199-89-0.mol
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4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Chemical Properties

Melting point:
97-99 °C(lit.)
Boiling point:
333.1±45.0 °C(Predicted)
Density 
2.0589 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform.
pka
-5.65±0.50(Predicted)
form 
Crystalline Powder
color 
Yellow to light brown
Water Solubility 
soluble
BRN 
614212
CAS DataBase Reference
10199-89-0(CAS DataBase Reference)
EPA Substance Registry System
2,1,3-Benzoxadiazole, 4-chloro-7-nitro- (10199-89-0)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/38
Safety Statements 
36/37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
DF8002400
10-21
TSCA 
Yes
HS Code 
29349990

MSDS

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4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Usage And Synthesis

Chemical Properties

yellow to light brown crystalline powder

Uses

4-Chloro-7-nitrobenzofurazan is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. 4-Chloro-7-nitrobenzofurazan has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines.

Uses

A fluorescent reagent

Definition

ChEBI: A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorine and at position 7 by a nitro group.

Purification Methods

Wash the solid with H2O, and it recrystallises from aqueous EtOH (1:1) as pale yellow needles. It sublimes in a vacuum [Gosh & Whitehouse Biochem J 108 155 1968, UV, NMR: Bolton et al. J Chem Soc 1004 1966].

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4-Chloro-7-nitrobenzo-2-oxa-1,3-diazoleSupplierMore

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