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Lycopene

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Lycopene Basic information

Product Name:
Lycopene
CAS:
502-65-8
MF:
C40H56
MW:
536.87
EINECS:
207-949-1
Mol File:
502-65-8.mol
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Lycopene Chemical Properties

Melting point:
172-173°C
Boiling point:
644.94°C (rough estimate)
Density 
0.9380 (estimate)
FEMA 
4110 | TOMATO LYCOPENE
refractive index 
1.5630 (estimate)
storage temp. 
−70°C
form 
powder
Stability:
Heat sensitive - store at -70 C. Combustible. Incompatible with strong oxidizing agents.
InChIKey
OAIJSZIZWZSQBC-BOJOQWLHSA-N
CAS DataBase Reference
502-65-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
8-10-23
HS Code 
32030019

MSDS

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Lycopene Usage And Synthesis

Chemical Properties

Pink Powder

Chemical Properties

White to pale-yellow solid; balsam oriental aroma.

Occurrence

Lycopene is a carotenoid that occurs naturally in tomatoes.

Uses

Carotenoid antioxidant occurring in ripe fruit, especially in tomatoes.

Definition

ChEBI: An acyclic carotene commonly obtained from tomatoes and other red fruits.

Aroma threshold values

Medium strength odor, balsamic type; recommend smelling in a 1.0% solution or less.

Anticancer Research

Lycopene is a naturally occurring chemical that manifests as a red pigment contained in common foods such as tomatoes, pink grapefruits, guava, and watermelon (Giovannucci 1999). This is a very strong antioxidant that has been found to prevent and even reverse the progression of prostate cancer, as well as treating benign prostatic hyperplasia. In a recent study, 30 mg a day of lycopene showed curative results in prostate cancer. For best results, supplements are recommended alongside eating and drinking plenty of lycopene-containing food and juices (Jatoi et al. 2007). Earlier research showed that taking a specific combination of lycopene, selenium, and saw palmetto by mouth for 8 weeks reduced pain in men with prostate swelling and pelvic pain more significantly than saw palmetto alone (Feifer et al. 2002).Lycopene shows anticancer activity against prostate, endometrial, breast, and colon carcinomas. It inhibits human cancer cell proliferation by activation of cancer-preventive enzymes like phase II detoxification enzymes, by suppression of insulin-like growth factor-I-stimulated growth (Wang et al. 2012). It also activates antioxidant enzymes like GST, GSH, and GPx and protects from oxidative stress caused by carcinogens. It alters PI3K/AKT pathway and ERK and Bcl-2 signaling in pancreatic and gastric carcinoma cells, respectively (Singh et al. 2016b).

Purification Methods

Crystallise lycopene from CS2/MeOH, diethyl ether/pet ether, or acetone/pet ether. Also purify it by column chromatography on deactivated alumina, CaCO3, calcium hydroxide or magnesia. It is oxygen sensitive and is stored in the dark, in an inert atmosphere. Also purified like -Carotene. [Beilstein 1 III 1076, 1 IV 1165.]

Lycopene Preparation Products And Raw materials

Raw materials

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LycopeneSupplierMore

Puripharm Co., Ltd. Gold
Tel:
0572-2745768-1;0572-2717806-
Email:
sales@puripharm.com;yzm@puripharm.com
Shijiazhuang jianhe biotechnology co. LTD Gold
Tel:
0311-83506700
Email:
export@jh-biotech.com
Nanjing Duolong Bio-tech Co.,Ltd. Gold
Tel:
Email:
sales@dolonchem.com
Speranza Chemical Co., Ltd. Gold
Tel:
0755-33122716 18688942810
Email:
sales@speranzachem.com
Nanjing Ally Chemical S&T Co., Ltd. Gold
Tel:
025-58367986
Email:
3209878052@qq.com
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