Lycopene Chemical Properties
- Melting point:
- Boiling point:
- 644.94°C (rough estimate)
- 0.9380 (estimate)
- 4110 | TOMATO LYCOPENE
- refractive index
- 1.5630 (estimate)
- storage temp.
- Heat sensitive - store at -70 C. Combustible. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 502-65-8(CAS DataBase Reference)
Lycopene Usage And Synthesis
White to pale-yellow solid; balsam oriental aroma.
Lycopene is a carotenoid that occurs naturally in tomatoes.
Carotenoid antioxidant occurring in ripe fruit, especially in tomatoes.
ChEBI: An acyclic carotene commonly obtained from tomatoes and other red fruits.
Aroma threshold values
Medium strength odor, balsamic type; recommend smelling in a 1.0% solution or less.
Lycopene is a naturally occurring chemical that manifests as a red pigment contained in common foods such as tomatoes, pink grapefruits, guava, and watermelon (Giovannucci 1999). This is a very strong antioxidant that has been found to prevent and even reverse the progression of prostate cancer, as well as treating benign prostatic hyperplasia. In a recent study, 30 mg a day of lycopene showed curative results in prostate cancer. For best results, supplements are recommended alongside eating and drinking plenty of lycopene-containing food and juices (Jatoi et al. 2007). Earlier research showed that taking a specific combination of lycopene, selenium, and saw palmetto by mouth for 8 weeks reduced pain in men with prostate swelling and pelvic pain more significantly than saw palmetto alone (Feifer et al. 2002).Lycopene shows anticancer activity against prostate, endometrial, breast, and colon carcinomas. It inhibits human cancer cell proliferation by activation of cancer-preventive enzymes like phase II detoxification enzymes, by suppression of insulin-like growth factor-I-stimulated growth (Wang et al. 2012). It also activates antioxidant enzymes like GST, GSH, and GPx and protects from oxidative stress caused by carcinogens. It alters PI3K/AKT pathway and ERK and Bcl-2 signaling in pancreatic and gastric carcinoma cells, respectively (Singh et al. 2016b).
Crystallise lycopene from CS2/MeOH, diethyl ether/pet ether, or acetone/pet ether. Also purify it by column chromatography on deactivated alumina, CaCO3, calcium hydroxide or magnesia. It is oxygen sensitive and is stored in the dark, in an inert atmosphere. Also purified like -Carotene. [Beilstein 1 III 1076, 1 IV 1165.]
Lycopene Preparation Products And Raw materials
- CAROTENOID MIXED STANDARD 500UL(SH)
- Sennoside A
- Black garlic extract
- Tomato P.E
- lycopene cyclase-isomerase
- LYCOPENE(PRIMARY STANDARD)
- LYCOPENE(SECONDARY STANDARD)
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