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Ampicillin Structure

Ampicillin

Chemical Properties

Melting point 208 °C (dec.)(lit.)
Boiling point 684℃
refractive index  265 ° (C=0.1, H2O)
Flash point 87 °C
storage temp.  Sealed in dry,2-8°C
solubility  NH4OH 1 M: 50 mg/mL, clear, colorless
form  solid
color  white to off-white
pka 2.5 (COOH)(at 25℃)
Water Solubility  0.1-1 g/100 mL at 21 ºC
Merck  14,586
BRN  5399534
Stability Hygroscopic
InChIKey RXDALBZNGVATNY-CWLIKTDRSA-N
CAS DataBase Reference 7177-48-2(CAS DataBase Reference)
EPA Substance Registry System Ampicillin trihydrate (7177-48-2)
As a penicillin group of beta-lactam antibiotics, Ampicillin is the first broad-spectrum penicillin, which has in vitro activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, commonly used for preventing and treating bacterial infections of respiratory tract, urinary tract, middle ear, sinuses, stomach and intestines, bladder, and kidney, etc. caused by susceptible bacteria. It is also used to treat uncomplicated gonorrhea, meningitis, endocarditis salmonellosis, and other serious infections through administered by mouth, intramuscular injection or by intravenous infusion. Like all antibiotics, it is not effective for the treatment of viral infections.

Safety Information

Hazard Codes  Xn,Xi
Risk Statements  36/37/38-42/43
Safety Statements  22-26-36/37-36-45-23
WGK Germany  2
RTECS  XH8425000
3-10
HS Code  29411020
Toxicity LD50 orl-rat: 10 g/kg ANTBAL 20,653,75

MSDS

Usage And Synthesis

Preparation Products And Raw materials

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