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Imperatorin

Basic information Description References Safety Related Supplier

Imperatorin Basic information

Product Name:
Imperatorin
CAS:
482-44-0
MF:
C16H14O4
MW:
270.28
EINECS:
207-581-1
Mol File:
482-44-0.mol
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Imperatorin Chemical Properties

Melting point:
98-100°C
Boiling point:
333.4°C (rough estimate)
Density 
1.1311 (rough estimate)
refractive index 
1.4350 (estimate)
storage temp. 
2-8°C
solubility 
DMSO: ≥5mg/mL
form 
powder
color 
off-white to light brown
λmax
301nm(MeOH)(lit.)
Merck 
14,4925
InChIKey
OLOOJGVNMBJLLR-UHFFFAOYSA-N
CAS DataBase Reference
482-44-0(CAS DataBase Reference)
NIST Chemistry Reference
7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LV1575000
HS Code 
29419090
Hazardous Substances Data
482-44-0(Hazardous Substances Data)
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Imperatorin Usage And Synthesis

Description

Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.

References

https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin

Chemical Properties

White Solid

Definition

ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.

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ImperatorinSupplierMore

ShangHai YuanYe Biotechnology Co., Ltd. Gold
Tel:
15800763013 021-61312847-
Email:
3008007399@qq.com
Products Intro:
Product Name:Imperatorin
CAS:482-44-0
Purity:HPLC≥98% Package:20mg
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro:
Product Name:Imperatorin, 98%
CAS:482-44-0
Purity:98% Package:10MG;50MG
Chembest Research Laboratories Limited
Tel:
021-20908456-
Email:
sales@BioChemBest.com
Products Intro:
Product Name:MARMELOSIN (IMPERATORIN)
CAS:482-44-0
Remarks:C11428
Chemsky(shanghai)International Co.,Ltd.
Tel:
021-50135380
Email:
shchemsky@sina.com
Products Intro:
Product Name:IMperatorin
CAS:482-44-0
Purity:98%
Chengdu XiYa Chemical Technology Co., Ltd.
Tel:
400-990-3999
Email:
sale@xiyashiji.com;3007716753@qq.com
Products Intro:
CAS:482-44-0
Purity:98% (HPLC) Package:25g;100g;500g;1kg
Basic information Description References Safety Related Supplier