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1,1-Dichloro-2,2,2-trifluoroethane

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1,1-Dichloro-2,2,2-trifluoroethane Basic information

Product Name:
1,1-Dichloro-2,2,2-trifluoroethane
CAS:
306-83-2
MF:
C2HCl2F3
MW:
152.93
EINECS:
206-190-3
Mol File:
306-83-2.mol
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1,1-Dichloro-2,2,2-trifluoroethane Chemical Properties

Melting point:
-107°C
Boiling point:
27.6°C
Density 
1,475 g/cm3
refractive index 
1.3290
Flash point:
9℃
storage temp. 
2-8°C
form 
A liquid
CAS DataBase Reference
306-83-2(CAS DataBase Reference)
NIST Chemistry Reference
Ethane, 2,2-dichloro-1,1,1-trifluoro-(306-83-2)
EPA Substance Registry System
HCFC-123 (306-83-2)
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Safety Information

Hazard Codes 
T,Xi,N
Risk Statements 
23/24/25-39-39/23/24/25-59
Safety Statements 
36/37-45-59
RIDADR 
3163
WGK Germany 
1
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, GAS, OZONE DEPLETER
Hazardous Substances Data
306-83-2(Hazardous Substances Data)
Toxicity
LD50 skin in rabbit: > 2gm/kg

MSDS

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1,1-Dichloro-2,2,2-trifluoroethane Usage And Synthesis

Chemical Properties

1,1-Dichloro-2,2,2-trifluoroethane has a light ethereal odor with poor warning properties.

Uses

HCFC 123 is an interim replacement for the CFCs and is scheduled for a production phase-out during the 2020s. Its main application is as a substitute for CFC 11 in centrifugal chillers used for air conditioning of large buildings. It is also used in smaller air-conditioning units, and may have applications in foam blowing, and firefighting and as a chemical intermediate.

General Description

Colorless nonflammable gas. Nearly odorless.

Reactivity Profile

1,1-Dichloro-2,2,2-trifluoroethane is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. They suffer oxidation with strong oxidizing agents and under extremes of temperature.

Health Hazard

HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) has evidenced significant human liver toxicity. A group of 17 workers suffered liver damage in a 1997 outbreak. They were involved in containerizing this liquid. HCFC-123 is chemically similar to halothane and has the same toxic metabolite. HCFC- 123 exposure also was implicated as the cause of liver disease in nine industrial workers who had repeated exposure because of a leaking airconditioning system in 1996; the refrigerant also contained HCFC-124. HCFC-124 and HCFC-125 are also structurally similar to halothane.

Safety Profile

Suspected carcinogen. Moderately toxic by inhalation. When heated to decomposition it emits very toxic fumes of Fand Cl-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and FLUORIDES.

Carcinogenicity

An inhalation toxicity/oncogenicity study was conducted with groups of 80 male and 80 female rats. This study was described earlier in this section. In addition to the effects on serum chemistry parameters and the retina, increases in benign tumors of the pancreas, testes, and liver were reported. As noted above, the survival in the HCFC 123–exposed animals was better than in the airexposed controls. These tumors tended to appear near the end of the study and generally were not considered to be the cause of death.

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1,1-Dichloro-2,2,2-trifluoroethaneSupplierMore

J & K SCIENTIFIC LTD.
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Clearsynth Labs Limited
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+91-22-26355700
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