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Tributyrin

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Tributyrin Basic information

Product Name:
Tributyrin
CAS:
60-01-5
MF:
C15H26O6
MW:
302.36
EINECS:
200-451-5
Mol File:
60-01-5.mol
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Tributyrin Chemical Properties

Melting point:
-75 °C
Boiling point:
305 °C
Density 
1.0335
FEMA 
2223 | (TRI-)BUTYRIN
refractive index 
n20/D 1.435(lit.)
Flash point:
345 °F
storage temp. 
Store at RT.
solubility 
H2O: insoluble
form 
Liquid
color 
Clear colorless to yellow
Water Solubility 
Not miscible in water.
JECFA Number
922
Merck 
14,9620
BRN 
1714746
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
UYXTWWCETRIEDR-UHFFFAOYSA-N
CAS DataBase Reference
60-01-5(CAS DataBase Reference)
EPA Substance Registry System
Tributyrin (60-01-5)
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Safety Information

Safety Statements 
24/25
WGK Germany 
1
RTECS 
ET7350000
TSCA 
Yes
HS Code 
29171900

MSDS

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Tributyrin Usage And Synthesis

Description

§ 184.1903(a) Tributyrin (C15H26O6), also known as butyrin or glyceryl tributyrate, is the triester of glycerin and butyric acid. It is prepared by esterifcation of glycerin with excess butyric acid. Glycerol tributyrate has a characteristic odor and a bitter taste.

Chemical Properties

Glycerol tributyrate has a characteristic odor and bitter taste.

Chemical Properties

colourless liquid

Chemical Properties

Tributyrin is a colorless, oily liquid with a bitter taste. It is soluble in alcohol and ether and fairly insoluble in water.

Uses

Tributyrin is a flavoring agent that is the triester of glycerin and butyric acid. it is prepared by esterification of glycerin with excess butyric acid. it is used in the following foods: baked goods; alcoholic beverages; nonalcoholic beverages; fats and oils; frozen dairy des- serts and mixes; gelatins, puddings and fillings; and soft candy. it is also termed butyrin and glyceryl tributyrate.

Uses

Plasticizer, flavoring.

Definition

ChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid.

Preparation

Prepared by esterifcation of glycerol with excess butyric acid.

Production Methods

Tributyrin is manufactured via esterification of glycerol with butyric acid.

Taste threshold values

Taste characteristics at 30 ppm: bitter, waxy, fatty, cheese and butter nuances.

Safety Profile

Poison by intravenous route. Low toxicity by ingestion. Questionable carcinogen with experimental tumorigenic data. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS

Carcinogenicity

Administration of sodium butyrate in drinking water potentiates 1,2-dimethylhydrazine- induced colon cancer in rats . In mice, dietary administration of 5% tributyrin for 48 weeks did not lead to an increase in colonic tumor incidence or focal areas of dysplasia as compared to controls . Therefore, it has been suggested that the agent responsible for enhanced tumorigenesis in the rat study was sodium, rather than butyrate.

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TributyrinSupplierMore

Shanghai Dingfen Chemical Technology Co., Ltd. Gold
Tel:
021-37590756-
Email:
373600283@qq.com
Nanjing songguan Biotechnology Co., Ltd. Gold
Tel:
025-52168336
Email:
2714748392@qq.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
future industrial shanghai co., ltd
Tel:
400-0066-400;021-60496031
Email:
sales@jonln.com;sales@jonln.com
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