Tributyrin Chemical Properties
- Melting point:
- -75 °C
- Boiling point:
- 305 °C
- 2223 | (TRI-)BUTYRIN
- refractive index
- Flash point:
- 345 °F
- storage temp.
- Store at RT.
- H2O: insoluble
- Clear colorless to yellow
- Water Solubility
- Not miscible in water.
- JECFA Number
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 60-01-5(CAS DataBase Reference)
- EPA Substance Registry System
- Tributyrin (60-01-5)
- Safety Statements
- WGK Germany
- HS Code
Tributyrin Usage And Synthesis
§ 184.1903(a) Tributyrin (C15H26O6), also known as butyrin or glyceryl tributyrate, is the triester of glycerin and butyric acid. It is prepared by esterifcation of glycerin with excess butyric acid. Glycerol tributyrate has a characteristic odor and a bitter taste.
Glycerol tributyrate has a characteristic odor and bitter taste.
Tributyrin is a colorless, oily liquid with a bitter taste. It is soluble in alcohol and ether and fairly insoluble in water.
Tributyrin is a flavoring agent that is the triester of glycerin and butyric acid. it is prepared by esterification of glycerin with excess butyric acid. it is used in the following foods: baked goods; alcoholic beverages; nonalcoholic beverages; fats and oils; frozen dairy des- serts and mixes; gelatins, puddings and fillings; and soft candy. it is also termed butyrin and glyceryl tributyrate.
ChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid.
Prepared by esterifcation of glycerol with excess butyric acid.
Tributyrin is manufactured via esterification of glycerol with butyric acid.
Taste threshold values
Taste characteristics at 30 ppm: bitter, waxy, fatty, cheese and butter nuances.
Poison by intravenous route. Low toxicity by ingestion. Questionable carcinogen with experimental tumorigenic data. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS
Administration of sodium butyrate in drinking water potentiates 1,2-dimethylhydrazine- induced colon cancer in rats . In mice, dietary administration of 5% tributyrin for 48 weeks did not lead to an increase in colonic tumor incidence or focal areas of dysplasia as compared to controls . Therefore, it has been suggested that the agent responsible for enhanced tumorigenesis in the rat study was sodium, rather than butyrate.
- GLYCEROL TRIVALERATE
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