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Oxandrolone

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Oxandrolone Basic information

Product Name:
Oxandrolone
CAS:
53-39-4
MF:
C19H30O3
MW:
306.44
EINECS:
200-172-9
Mol File:
53-39-4.mol
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Oxandrolone Chemical Properties

Melting point:
235-238°C
alpha 
D25 -23° (c = approx 1% in chloroform)
Boiling point:
387.04°C (rough estimate)
Density 
1.0829 (rough estimate)
refractive index 
1.4200 (estimate)
storage temp. 
Controlled Substance, -20?C Freezer
solubility 
DMSO: soluble2mg/mL (clear solution; warmed)
pka
15.15±0.60(Predicted)
form 
powder
color 
white to beige
optical activity
[α]/D -19 to -26°, c = 1 (CDCl3)
Merck 
6921
InChIKey
QSLJIVKCVHQPLV-PEMPUTJUSA-N
CAS DataBase Reference
53-39-4(CAS DataBase Reference)
NIST Chemistry Reference
Oxandrolone(53-39-4)
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Safety Information

Hazard Codes 
T
Risk Statements 
60-63-20/21/22
Safety Statements 
22-36/37/39-45
WGK Germany 
3
RTECS 
RN6800700
HS Code 
2937290000
Hazardous Substances Data
53-39-4(Hazardous Substances Data)
Toxicity
LD50 oral in rabbit: > 5gm/kg
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Oxandrolone Usage And Synthesis

Description

Oxandrolone is a synthetic anabolic-androgenic steroid. It is a 17 alpha-methylated version of dihydrotestosterone (DHT). It can be used for the treatment of many kinds of disorders such as idiopathic short stature, body mass loss due to catabolic illness, severe burns, trauma and hereditary angioedema as well as turner syndrome. Oxandrolone is especially effective in the treatment of severe burns without causing obvious side effects. It acts as an agonist of the androgen receptor, which modulates related gene expression to increase protein synthesis, further boosting muscle growth and increasing body mass as well as bone mineral density. However, it should be noted that its androgenic effect is less than its anabolic effect.

Chemical Properties

White Solid

Uses

androgenic anabolic steroid;reverses catabolic tissue processes; promotes buildup of protein; increases erythropoietin production

Uses

A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.

brand name

Oxandrin (Savient).

General Description

Oxandrolone, 17β-hydroxy-17-methyl-2-oxaandrostan-3-one, is approved to aid in the promotionof weight gain after weight loss following surgery,chronic infections, or severe trauma and to offset protein catabolismassociated with long-term corticosteroid use.Oxandrolone is also used to relieve bone pain accompanyingosteoporosis. It has been used to treat alcoholic hepatitisand HIV wasting syndrome.

Safety Profile

Moderately toxic by ingestion andintraperitoneal routes. Experimental reproductive effects.When heated to decomposition it emits acrid smoke andfumes.

References

Li, H., et al. "The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis. " Burns Journal of the International Society for Burn Injuries 42.4(2016): 717.
Hart, D. W., et al. "Anabolic effects of oxandrolone after severe burn." Annals of Surgery 233.4(2001): 556-564.
Sheffieldmoore, M, et al. "Short-term oxandrolone administration stimulates net muscle protein synthesis in young men. " Journal of Clinical Endocrinology & Metabolism 84.8(1999): 2705-11.
https://en.wikipedia.org/wiki/Oxandrolone

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OxandroloneSupplierMore

HuBei ShengBaoLai Biological Technology Co., Ltd Gold
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027-59105235-
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Wuhan Biocar Bio-Pharm Co., Ltd. Gold
Tel:
86 15387057351
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sales@biocar.cn
Wuhan Runzeweiye Technology Co., Ltd. Gold
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027-50779735-
Email:
runzeweiye999@163.com;
Rixing Chemical CO.,LTD. Gold
Tel:
13237129059
Email:
info@rixingchemi.com
Taizhou Xinen biotechnology Co.,Ltd Gold
Tel:
;
Email:
420524779@qq.com;singsteroid@163.com
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