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Albuterol sulfate

Basic information Description References Safety Related Supplier

Albuterol sulfate Basic information

Product Name:
Albuterol sulfate
CAS:
51022-70-9
MF:
C13H23NO7S
MW:
337.39
EINECS:
256-916-8
Mol File:
51022-70-9.mol
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Albuterol sulfate Chemical Properties

Melting point:
180 °C
Flash point:
250 °C
storage temp. 
Store at RT
solubility 
1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green
form 
neat
Water Solubility 
Soluble in water and 1M sodium hydroxide (50 mg/ml).
Merck 
216
InChIKey
OVICLFZZVQVVFT-UHFFFAOYSA-N
CAS DataBase Reference
51022-70-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
43-22
Safety Statements 
36/37-36
RIDADR 
2811
WGK Germany 
3
RTECS 
ZE4400000
HS Code 
29225090

MSDS

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Albuterol sulfate Usage And Synthesis

Description

Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.

References

https://en.wikipedia.org/wiki/Salbutamol
https://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm

Chemical Properties

White Crystalline Solid

Uses

?Adrenergic agonist

Uses

A β2-adrenoceptor agonist. Bronchodilator; tocolytic.

Uses

Bronchodilator, antiasthmatic

brand name

Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).

Biological Activity

Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.

Veterinary Drugs and Treatments

Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.

Albuterol sulfate Preparation Products And Raw materials

Raw materials

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Albuterol sulfateSupplierMore

Shanghai Boyle Chemical Co., Ltd. Gold
Tel:
Email:
sales@boylechem.com
Nanjing LuoDa Chemical Co., Ltd Gold
Tel:
025-66016961-
Email:
sales@chemluo.com;
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
INTATRADE GmbH
Tel:
+49 3493/605464
Email:
sales@intatrade.de
Basic information Description References Safety Related Supplier