Albuterol sulfate Chemical Properties
- Melting point:
- 180 °C
- Flash point:
- 250 °C
- storage temp.
- Store at RT
- 1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green
- Water Solubility
- Soluble in water and 1M sodium hydroxide (50 mg/ml).
- CAS DataBase Reference
- 51022-70-9(CAS DataBase Reference)
Albuterol sulfate Usage And Synthesis
Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.
White Crystalline Solid
A β2-adrenoceptor agonist. Bronchodilator; tocolytic.
Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).
Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.
Veterinary Drugs and Treatments
Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.
Albuterol sulfate Preparation Products And Raw materials
- Benzyl alcohol
- Vanadyl sulfate
- Albuterol sulfate
- D-Glucosamine sulfate
- 4-Hydroxybenzyl alcohol
- Ethyl acetate
- n-Dodecyl alcohol, sulfated
- CHLOROPHOSPHONAZO III
- Sodium sulfate
- Aluminum sulfate
- Magnesium sulfate heptahydrate
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