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2-Bromoacetophenone

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2-Bromoacetophenone Basic information

Product Name:
2-Bromoacetophenone
CAS:
70-11-1
MF:
C8H7BrO
MW:
199.04
EINECS:
200-724-9
Mol File:
70-11-1.mol
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2-Bromoacetophenone Chemical Properties

Melting point:
48-51 °C(lit.)
Boiling point:
135 °C18 mm Hg(lit.)
Density 
1.476
refractive index 
1.5700 (estimate)
Flash point:
>230 °F
storage temp. 
2-8°C
form 
Crystals or Powder
color 
White to dark green-brown
Water Solubility 
PRACTICALLY INSOLUBLE
Merck 
14,1402
BRN 
606474
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKey
LIGACIXOYTUXAW-UHFFFAOYSA-N
CAS DataBase Reference
70-11-1(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 2-bromo-1-phenyl-(70-11-1)
EPA Substance Registry System
Ethanone, 2-bromo-1-phenyl- (70-11-1)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-20/21/22
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2645 6.1/PG 2
WGK Germany 
3
8-19
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29143990

MSDS

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2-Bromoacetophenone Usage And Synthesis

Chemical Properties

Off white-grey green crystaline powder

Uses

2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors

Uses

Preparation of crystalline esters from acids

Definition

ChEBI: An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.

General Description

A crystalline solid or a liquid with a sharp odor. Toxic by inhalation, ingestion and skin absorption. A severe eye irritant (a lachrymator). Used to make other chemicals.

Air & Water Reactions

Reacts slowly with moisture in air to form hydrogen bromide.

Reactivity Profile

2-Bromoacetophenone reacts slowly with metals causing mild corrosion.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Purification Methods

Crystallise the bromide from EtOH, MeOH or pet ether (b 80-100o). [Tanner J Org Chem 52 2142 1987, Beilstein 7 IV 649.]

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2-BromoacetophenoneSupplierMore

Alfa Aesar Gold
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400-610-6006; 021-67582000
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Changzhou Jiang Xing Chemical Co., Ltd. Gold
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Shijiazhuang Als Pharmaceutical Technology Co., Ltd. Gold
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0311-85150550 18932901920
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Weifang QianJin Fine Chemical Co., Ltd. Gold
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1577399715@qq.com
J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
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