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Zinc pyrithione

Basic information Product description Uses Safety Related Supplier

Zinc pyrithione Basic information

Product Name:
Zinc pyrithione
CAS:
13463-41-7
MF:
C10H8N2O2S2Zn
MW:
317.7
EINECS:
236-671-3
Mol File:
13463-41-7.mol
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Zinc pyrithione Chemical Properties

Melting point:
approximate 240℃
Density 
1.782 g/cm3(Temp: 25 °C)
Water Solubility 
Insoluble (<0.1 g/100 mL at 21 ºC)
Merck 
14,7994
InChIKey
OTPSWLRZXRHDNX-UHFFFAOYSA-L
CAS DataBase Reference
13463-41-7(CAS DataBase Reference)
EPA Substance Registry System
Zinc pyrithione (13463-41-7)
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Safety Information

Hazard Codes 
T+,N,T
Risk Statements 
24/25-26-37/38-41-50/53-23-22
Safety Statements 
26-28-36/37/39-45-61-60-39
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
ZH0950000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29333990
Hazardous Substances Data
13463-41-7(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 177mg/kg

MSDS

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Zinc pyrithione Usage And Synthesis

Product description

Also known as zinc Omadine ,this pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent. At room temperature it is white to yellow crystalline powder. Slight characteristic odor. Insoluble in water. Solubility: water 15mg/kg; pH = 8 Water 35mg/kg; Ethanol 100mg/kg; polyethylene glycol (PEG400) 2000mg/kg. A pH optimum range of 4.5 to 9.5; mass fraction of 10% suspension pH3.6. Zinc pyrithione react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures ,it is not stable to acids and bases . It is not compatible with EDTA, non-ionic surfactants make it partially deactivated. When with the presence of heavy metals, chelation or anti-sequestration will occur, and these chelates are insoluble in water.
EEC and GB7916-87 provide that maximum allowable concentration of mass fraction of zinc pyrithione on cosmetics is 0.5%, only for cleaning after using products.General concentration 250~1000mg/kg (active), zinc pyrithione can be used in gels, creams, lotions, talcum powder and anti-dandruff shampoo, deodorant and also for disinfecting articles.
The above information is edited by the Chemicalbook of Tian Ye.

Uses

Shampoo for dandruff,zinc pyrithione can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation. zinc pyrithion is also used as a cosmetic preservative, oil, paint biocide.
Zinc pyrithione has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .

Chemical Properties

Beige granules

Uses

antibacterial (urinary)

Uses

zinc pyrithione is a preservative against bacteria, fungi, and yeast. It is unstable in light and in the presence of oxidizing agents. Zinc pyrithione is useful in gels, creams, heavy lotions, and talcum powder.

brand name

Head & Shoulders Conditioner (Procter & Gamble).

General Description

Fine beige granules.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Organometallics, such as Zinc pyrithione, are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases.

Fire Hazard

Flash point data for Zinc pyrithione are not available, but Zinc pyrithione is probably combustible.

Contact allergens

Zinc pyrithione is widely used in antidandruff shampoos and is a classic allergen. Concomitant reactions are expected to both zinc and sodium pyrithione.

Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx, SOx, and ZnO. Used as an anti- dandruff agent in shampoos. See also ZINC COMPOUNDS and SULFIDES.

Zinc pyrithione Preparation Products And Raw materials

Preparation Products

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Zinc pyrithioneSupplierMore

WUXI HONORSHINE CHEMICAL CO.,LTD. Gold
Tel:
0510-83593312-
Email:
sales@honorshinechem.com;
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Energy Chemical
Tel:
021-58432009
Email:
sales8178@energy-chemical.com
Basic information Product description Uses Safety Related Supplier