Aluminum monostearate is an aluminum compound of stearic acid
and palmitic acid. The USP32–NF27 states that aluminum
monostearate contains the equivalent of not less than 14.5% and
not more than 16.5% of Al2O3, calculated on the dried basis. The
JP XV states that it contains not less than 7.2% and not more than
8.9% of aluminium.
Aluminum monostearate occurs as a white, fine, bulky powder
with a slight odor of fatty acid. It is a solid material.
Fine, white to yellowish-white powder; faint characteristic odor. Insoluble in water, alcohol, and ether. Forms a gel with aliphatic and aromatic hydrocarbons.
Paints, inks, greases, waxes, thickening lubricating oils; waterproofing, gloss producer, stabilizer for plastics, food additive.
Used for the packaging of pharmaceuticals, and in the preparation of colors for cosmetics.
Aluminum monostearate is prepared by reacting aluminum with
stearic acid.
A complex containing aluminum and dextran, a chain of molecular weight 2500, corresponding to a chain of 15 anhydroglucose units.
Pharmaceutical Applications
Aluminum monostearate is mainly used in microencapsulation
and in the manufacture of ointments. Aluminum monostearate is
used as a viscosity-increasing agent in nonaqueous cosmetic and
pharmaceutical formulations. In addition, aluminum monostearate
can be used as an emulsion stabilizer in cosmetic emulsions and is
used in cosmetics such as mascara, moisturizers, and sunscreens.
A nuisance dust. When heated to decomposition it emits acrid smoke and fumes. See also ALUMINUM COMPOUNDS.
Aluminum monostearate is generally regarded as relatively nontoxic
and nonirritant when used as an excipient.
Aluminum monostearate should be stored in a well-closed container
in a cool, dry, place. It is stable under ordinary conditions of use and
storage.
Aluminum monostearate and aluminum stearate are included in the
FDA Inactive Ingredients Database (oral capsules and tablets,
topical creams and ointments). Included in nonparenteral medicines
licensed in the UK.
