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Amiodarone hydrochloride

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Amiodarone hydrochloride Basic information

Product Name:
Amiodarone hydrochloride
CAS:
19774-82-4
MF:
C25H29I2NO3.ClH
MW:
681.77
EINECS:
243-293-2
Mol File:
19774-82-4.mol
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Amiodarone hydrochloride Chemical Properties

Melting point:
154-158°C
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Soluble in chloroform, methanol.
pka
pKa (25°C) 6.56 ±0.06
form 
neat
λmax
242nm(MeOH)(lit.)
Merck 
14,482
CAS DataBase Reference
19774-82-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,T,F
Risk Statements 
20/21/22-39/23/24/25-23/24/25-11
Safety Statements 
36-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
OB1361000
HS Code 
29322090
Hazardous Substances Data
19774-82-4(Hazardous Substances Data)

MSDS

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Amiodarone hydrochloride Usage And Synthesis

Chemical Properties

White Solid

Uses

Antiarrhythmic;Na+ channel blocker

Uses

A non-selective ion channel blocker. Antiarrhythmic (class III)

Veterinary Drugs and Treatments

Because of its potential toxicity and lack of experience with use in canine and equine patients, amiodarone is usually used when other less toxic or commonly used drugs are ineffective. It may be useful in dogs and horses to convert atrial fib into sinus rhythm and in dogs for arrhythmias associated with left ventricular dysfunction. In horses, one horse with Ventricular tachycardia was converted into sinus rhythm using amiodarone.
As the risk of sudden death is high in Doberman pinschers exhibiting rapid, wide-complex ventricular tachycardia or syncope with recurrent VPC’s, amiodarone may be useful when other drug therapies are ineffective.

Amiodarone hydrochloride Preparation Products And Raw materials

Preparation Products

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Amiodarone hydrochlorideSupplierMore

Nanjing Gold Pharmaceutical Technology Co. Ltd. Gold
Tel:
Email:
wgp@nanjing-pharmaceutical.com;wgp@nanjing-pharmaceutical.com;
Ningbo Disheng Chemical Co., Ltd. Gold
Tel:
0574-27862498
Email:
sales1@distant-chem.com
Shenzhen Kaimingke Biotechnology Co., Ltd. Gold
Tel:
181-26439142-
Email:
1144496688@QQ.COM;
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
INTATRADE GmbH
Tel:
+49 3493/605464
Email:
sales@intatrade.de
Basic information Safety Related Supplier