Basic information a cholesterol lowering agent General description Structure of statin compound Active Mechanism Medicinal Value Biosynthesis Uses Metabolism Precautions Adverse reaction Chemical property Uses Production method Safety Related Supplier
Lovastatin Structure

Lovastatin

Chemical Properties

Melting point 175°C
alpha  D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point 559.2±50.0 °C(Predicted)
Density  1.12±0.1 g/cm3(Predicted)
vapor pressure  0Pa at 25℃
refractive index  320 ° (C=0.5, CH3CN)
storage temp.  -20°C
solubility  ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
form  White to off-white powder
pka 13.49±0.40(Predicted)
color  White
Water Solubility  0.0004 mg/mL at 25 ºC
Merck  14,5586
BCS Class 2
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
LogP 4.260
CAS DataBase Reference 75330-75-5(CAS DataBase Reference)
EPA Substance Registry System Lovastatin (75330-75-5)

Safety Information

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-26
RIDADR  3077
WGK Germany  3
RTECS  EK7907000
HazardClass  9
PackingGroup  III
HS Code  29322090
Hazardous Substances Data 75330-75-5(Hazardous Substances Data)
Toxicity LD50 orally in mice: >1000 mg/kg (Endo)

Usage And Synthesis

Preparation Products And Raw materials

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