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Hydrocortisone acetate Structure

Hydrocortisone acetate

Chemical Properties

Melting point 223 °C (dec.)(lit.)
Boiling point 446.1°C (rough estimate)
alpha  D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone)
Density  d420 1.289
refractive index  1.4593 (estimate)
Flash point 223°C
storage temp.  0-6°C
solubility  Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride
pka 12.42±0.70(Predicted)
form  Solid
color  White to Off-White
Water Solubility  Insoluble in water.
Decomposition  223 ºC
Merck  14,4787
BRN  2066841
Stability Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
LogP 2.190
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone acetate(50-03-3)

Safety Information

Hazard Codes  Xn,T
Risk Statements  63-10-45
Safety Statements  36/37-45-53
WGK Germany  3
RTECS  GM8960000
HS Code  29372100
Toxicity LD50 intraperitoneal in mouse: 2300mg/kg

MSDS

Usage And Synthesis

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