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Quinaldine

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Quinaldine Basic information

Product Name:
Quinaldine
CAS:
91-63-4
MF:
C10H9N
MW:
143.19
EINECS:
202-085-1
Mol File:
91-63-4.mol
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Quinaldine Chemical Properties

Melting point:
-2 °C
Boiling point:
248 °C
Density 
1.058 g/mL at 25 °C(lit.)
vapor pressure 
<0.1 hPa (20 °C)
refractive index 
n20/D 1.612(lit.)
Flash point:
175 °F
storage temp. 
Store below +30°C.
solubility 
chloroform: soluble(lit.)
pka
5.83(at 20℃)
form 
Crystalline Powder
color 
White to slightly yellow
PH
6.9 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
PRACTICALLY INSOLUBLE
Sensitive 
Light Sensitive
Merck 
14,8047
BRN 
110309
Stability:
Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
91-63-4(CAS DataBase Reference)
NIST Chemistry Reference
Quinoline, 2-methyl-(91-63-4)
EPA Substance Registry System
Quinaldine (91-63-4)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
21/22-68-36/37/38
Safety Statements 
36-45-36/37/39-26
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
UZ9625000
8-23
TSCA 
Yes
HS Code 
29334990
Toxicity
LD50 orally in rats: 1.23 g/kg (Smyth)

MSDS

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Quinaldine Usage And Synthesis

Chemical Properties

yellowish-brown liquid

Uses

A useful ingredient in anti-malaria drugs, in manufacturing dyes, food colorants , pharmaceuticals and pH indicators.

Definition

ChEBI: A quinoline compound in which the quinoline skeleton is substituted at C-2 with a methyl group.

General Description

A colorless oily liquid darkening to red-brown on exposure to air. Flash point 175°F. Denser than water and slightly soluble in water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used to make dyes, pharmaceuticals and other chemicals.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Quinaldine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Keep tightly closed and protected from light .

Hazard

Strong irritant to mucous membranes.

Fire Hazard

Quinaldine is probably combustible.

Purification Methods

Dry it with Na2SO4 or by refluxing with BaO, then fractionally distil it under reduced pressure and redistil it from zinc dust. Purify it further by conversion to its phosphate (m 220o) or picrate (m 192o) from which after recrystallisation, the free base is regenerated. [Packer et al. J Am Chem Soc 80 905 1958.] Its ZnCl2 complex can be used for the same purpose. [Beilstein 20 III/IV 3454, 20 V 375.]

Quinaldine Preparation Products And Raw materials

Raw materials

Preparation Products

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QuinaldineSupplierMore

Tocopharm Co., Ltd. Gold
Tel:
021-69895597- ;021-69895597- ;021-69895597-
Email:
info@tocopharm.com;sales@tocopharm.com;739486509@qq.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
Alfa Aesar
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
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