Tween 80 Chemical Properties
- Boiling point:
- 1.08 g/mL at 20 °C
- vapor pressure
- <1 mm Hg ( 20 °C)
- refractive index
- 2917 | POLYSORBATE 80
- Flash point:
- >230 °F
- storage temp.
- Store at RT.
- viscous liquid
- Specific Gravity
- 1.080 (25/4℃)
- 5-7 (50g/l, H2O, 20℃)
- PH Range
- Water Solubility
- 5-10 g/100 mL at 23 ºC
- Hydrophilic-Lipophilic Balance (HLB)
- EPA Substance Registry System
- Polysorbate 80 (9005-65-6)
Tween 80 Usage And Synthesis
Tween 80, commonly known as polysorbate 80, is a synthetic compound that is widely applied in a variety of fields, including foods, medicines, and cosmetics. In food production, it is commonly used as a defoamer for the fermenting process of some wines and as a emulsifier in ice-cream or “puddings” to keep the creamy texture without separating. Tween 80 is also extensively applied in pharmaceutical industry, where it can be found in some vaccines, vitamins and supplements. It is an effective excipient to stabilize aqueous formulations of medications for parenteral administration and to improve the consistency of gel capsules, thus to make pills disperse in the stomach. Besides, it commonly serve as a surfactant and solubilizer in the production of soaps and cosmetics, which is effective to help dissolve ingredients and make products look creamier and more attractive. In laboratory, it is occasionally used for a test to identify the phenotype of a strain or isolate, such as mycobacteria.
Polysorbate 80 has a faint, characteristic odor and a warm, somewhat bitter taste. It is a mixture of oleate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides.
Yellow to amber liquid
Lonzest(R) SMO-20 is used as an emulsifier for textiles, personal care and industrial applications.
Lonzest(R) SMO-5 is a general purpose mid-range HLB, ethoxylated, nonionic surfactant suggested for use in textile chemicals (emulsifier, lubricant), household products and cosmetic formulations (o/w emulsifier, viscosity modifier).
Glycolube(R) AFA-1 is used as an antistat for PVC and as an antifog for PP, PE, PVC, PS.
Vinylube(R) 38 is an external lubricant for PVC bottle, film, and sheet components with excellent processing abilities and final clarity. It is also used as an antistatic agent. Product Data Sheet
Glycosperse(R) O-20 KFG is used as an emulsifier (ice cream, whipped topping) and as a solubilizing and dispersing agent in pickles and special vitamin-mineral preparations. Product Data Sheet
A non ionic detergent for cell lysis
As emulsifiers and dispersing agents in medicinal products; as defoamers and emulsifiers in foods. Pharmaceutic aid (surfactant).
ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by an oleoyl group.
Sorlate (Abbott); Tween 80 (ICI Americas).
Amber-colored viscous liquid. pH (5% aqueous solution) 5-7. Faint odor and bitter taste.
Air & Water Reactions
Tween 80 is incompatible with strong alkalis and oxidizers.
Tween 80 is probably combustible.
Moderately toxic by intravenous route. Mildly toxic by ingestion. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
- Span 80
- TERT-BUTYL ISOCYANIDE
- COBALT(II) ACETYLACETONATE
- 2,4-PENTANEDIONE, SILVER DERIVATIVE
- Aluminum acetylacetonate
- Ethyl isocyanoacetate
- COBALT ETHYLENE DIAMINE CHLORIDE
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- Cupric acetylacetonate
- BENZYL ISOCYANIDE
- Tosylmethyl isocyanide
- METHYL ISOCYANOACETATE