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5-Fluorouracil Structure

5-Fluorouracil

Chemical Properties

Melting point 282-286 °C (dec.) (lit.)
Boiling point 190-200°C/0.1mmHg
Density  1.4593 (estimate)
storage temp.  2-8°C
solubility  H2O: 10 mg/mL, clear
form  powder
pka pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain)
color  white
PH 4.3-5.3 (10g/l, H2O, 20℃)
Water Solubility  12.2 g/L 20 ºC
Sensitive  Air Sensitive
Merck  14,4181
BRN  127172
Stability Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey GHASVSINZRGABV-UHFFFAOYSA-N
CAS DataBase Reference 51-21-8(CAS DataBase Reference)
IARC 3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference 2,4-Pyrimidinedione, 5-fluoro-(51-21-8)
EPA Substance Registry System 5-Fluorouracil (51-21-8)

Safety Information

Hazard Codes  Xn,T,C,Xi
Risk Statements  22-20/21/22-52-25
Safety Statements  36-36/37-36/37/39-22-45-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YR0350000
10-23
Hazard Note  Irritant/Highly Toxic
TSCA  T
HazardClass  6.1
PackingGroup  III
HS Code  29335995
Hazardous Substances Data 51-21-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 230 mg/kg

MSDS

Usage And Synthesis

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