ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyridine compound >  Pyridine derivatives >  2-Picolinic acid

2-Picolinic acid

Basic information Safety Related Supplier

2-Picolinic acid Basic information

Product Name:
2-Picolinic acid
CAS:
98-98-6
MF:
C6H5NO2
MW:
123.11
EINECS:
202-719-7
Mol File:
98-98-6.mol
More
Less

2-Picolinic acid Chemical Properties

Melting point:
139-142 °C(lit.)
Boiling point:
229.19°C (rough estimate)
Density 
1.3147 (rough estimate)
refractive index 
1.5423 (estimate)
Flash point:
139°(232°F)
storage temp. 
Store at RT.
solubility 
H2O: 50 mg/mL, clear
pka
1.07(at 25℃)
form 
Crystalline Powder
color 
White to almost white
PH
3.1 (50g/l, H2O, 20℃)
Water Solubility 
887 g/L (20 ºC)
Merck 
14,7403
BRN 
109595
InChIKey
SIOXPEMLGUPBBT-UHFFFAOYSA-N
CAS DataBase Reference
98-98-6(CAS DataBase Reference)
NIST Chemistry Reference
2-Pyridinecarboxylic acid(98-98-6)
EPA Substance Registry System
2-Pyridinecarboxylic acid (98-98-6)
More
Less

Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36-36/37/38
Safety Statements 
26-36-33-24/25
WGK Germany 
3
RTECS 
TJ7344000
TSCA 
Yes
HS Code 
29333999
Hazardous Substances Data
98-98-6(Hazardous Substances Data)

MSDS

More
Less

2-Picolinic acid Usage And Synthesis

Chemical Properties

Off-white to tan powder

Uses

2-Picolinic acid is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.

Uses

Chelate for alkaline earth metals.1 Used to prepare picolinato ligated transition metal complexes.2,3,4

Definition

ChEBI: A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Purification Methods

Crystallise the acid from water or *benzene. The picrate has m 185-187o (from MeOH). [Beilstein 22 H 33, 22 I 502, 22 II 30, 22 III/IV 303, 22/2 V 3.]

More
Less

2-Picolinic acidSupplierMore

Suqian nanxiang chemical manufacturing co. LTD Gold
Tel:
21-39125199- ;21-39127448
Email:
sales@nanxiangchem.com;sales@nx-reagent.com;
Shanghai RC Chemicals Co. Ltd Gold
Tel:
86-21-50322175, 50322680
Email:
rcchemicals@vip.163.com,chad@rcc.net.cn
Dongyang Baihang Chemical Co., Ltd. Gold
Tel:
18006543966
Email:
355093164@qq.com
Anhui Dexinjia Biopharm Co., Ltd Gold
Tel:
0531-82375809-
Email:
maple@jndxj.com
Wuhan Rongcan Biotechnology Co., Ltd Gold
Tel:
Email:
2130026275@qq.com
Basic information Safety Related Supplier