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Methyl propionate

Basic information Description References Safety Related Supplier

Methyl propionate Basic information

Product Name:
Methyl propionate
CAS:
554-12-1
MF:
C4H8O2
MW:
88.11
EINECS:
209-060-4
Mol File:
554-12-1.mol
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Methyl propionate Chemical Properties

Melting point:
-88 °C
Boiling point:
79 °C(lit.)
Density 
0.915 g/mL at 25 °C(lit.)
vapor density 
3 (vs air)
vapor pressure 
40 mm Hg ( 11 °C)
refractive index 
n20/D 1.376(lit.)
FEMA 
2742 | METHYL PROPIONATE
Flash point:
43 °F
storage temp. 
Flammables area
solubility 
H2O: soluble16 parts
form 
Liquid
color 
Clear colorless
explosive limit
2.5-13%(V)
Water Solubility 
5 g/100 mL at 20 ºC
JECFA Number
141
Merck 
14,6112
BRN 
1737628
Stability:
Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, bases. Readily forms explosive mixtures with air. Moisture sensitive.
CAS DataBase Reference
554-12-1(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, methyl ester(554-12-1)
EPA Substance Registry System
Methyl propionate (554-12-1)
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Safety Information

Hazard Codes 
F,Xn
Risk Statements 
11-20-2017/11/20
Safety Statements 
16-24-29-33
RIDADR 
UN 1248 3/PG 2
WGK Germany 
1
RTECS 
UF5970000
Autoignition Temperature
876 °F
TSCA 
Yes
HS Code 
2915 50 00
HazardClass 
3
PackingGroup 
II
Hazardous Substances Data
554-12-1(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 5000 mg/kg

MSDS

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Methyl propionate Usage And Synthesis

Description

Methyl propionate is an organic compound belonging to the family of carboxylic acid esters, which is commonly applied as a solvent for cellulose nitrate and lacquers. It also serves as a raw material in organic synthesis for manufacturing paints, varnishes and other chemical productions such as methyl methacrylate. Besides, the fruity smell and taste of methyl propanoate results in its usage of fragrances and flavoring agents.
Methyl propanoate can be synthesized by esterifying propionic acid with methanol. In the field of industry, it is produced by the reaction of ethylene with carbon monoxide and methanol in the presence of nickel carbonyl.

References

https://en.wikipedia.org/wiki/Methyl_propionate
https://pubchem.ncbi.nlm.nih.gov/compound/11124#section=Top
https://www.alfa.com/zh-cn/catalog/A14944/

Description

Methyl propionate, also known as methyl propanoate, is a chemical compound with the molecular formula C4H8O2. It is a volatile ester with a sweet, fruity, rum-like odor.

Chemical Properties

colourless liquid

Chemical Properties

Methyl propionate is colorless liquid with a sweet, fruity, rum-like odor.

Chemical Properties

Methyl propionate has a fruity odor reminiscent of rum with a sweet flavor suggestive of black currant. May be prepared by direct esterification of the acid with methanol in the presence of concentrated H2S04.

Chemical Properties

Methyl propionate has a fruity odor reminiscent of rum. It has a sweet flavor suggestive of black currant

Occurrence

Reported found in guava, honey, melon, pineapple, raspberry, blackberry, strawberry, cheddar cheese, cooked beef, coffee, soy protein, durian (Durio zibethinus), starfruit, plum brandy, cherimoya, kiwifruit, naranjilla, mussels and rooibus tea (Aspalathus linearis)

Uses

Methyl propionate is used as a solvent for cellulose nitrate and lacquers, and as a raw material for the production of paints, varnishes and other chemicals such as methyl methacrylate.
Due to its fruity smell and taste, it is also used in fragrances and flavoring.

Uses

In organic synthesis.

Preparation

Methyl propionate can be prepared by esterification of propionic acid with methanol. Industrially, it is prepared by the reaction of ethylene with carbon monoxide and methanol in the presence of nickel carbonyl.

Production Methods

Methyl propionate is produced by the direct esterification of propionic acid with methanol in the presence of concentrated sulfuric acid .

Aroma threshold values

Detection: 100 ppb to 8.8 ppm

General Description

A clear colorless liquid. Flash point 28°F. Density about the same as water. Vapors heavier than air. May irritate skin, eyes, and mucous membranes. Used for flavoring and as a solvent.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Methyl propionate reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen is generated with alkali metals and hydrides.

Hazard

Flammable, dangerous fire risk, explosivelimits in air 2.5–13%.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by ingestion. Mildly toxic by inhalation. A skin irritant. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. Explosive in the form of vapor when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.

Chemical Synthesis

By direct esterification of the acid with methanol in the presence of concentrated H2SO4

Potential Exposure

Used as a solvent; and in making paints, lacquers, and varnishes. Also used in flavorings and fragrances

Shipping

UN1248 Methyl propionate, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Wash the ester with saturated aqueous NaCl, then dry it with Na2CO3 and distil it from P2O5. (This removes any free acid and alcohol.) It has also been dried with anhydrous CuSO4. [Beilstein 2 IV 104.]

Incompatibilities

May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Keep away from heat and moisture.

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Methyl propionateSupplierMore

Yangzhou shilihecheng Technology Co., Ltd Gold
Tel:
15312801805
Email:
545495101@qq.com
J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
Alfa Aesar
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Basic information Description References Safety Related Supplier