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4-Iodophenol

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4-Iodophenol Basic information

Product Name:
4-Iodophenol
CAS:
540-38-5
MF:
C6H5IO
MW:
220.01
EINECS:
208-745-5
Mol File:
540-38-5.mol
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4-Iodophenol Chemical Properties

Melting point:
92-94 °C(lit.)
Boiling point:
138 °C5 mm Hg(lit.)
Density 
1.8573
Flash point:
138°C/5mm
pka
9.33(at 25℃)
form 
Crystals or Crystalline Powder
color 
Pink or beige to brown
Water Solubility 
slightly soluble
Sensitive 
Light Sensitive
Merck 
14,5036
BRN 
1904544
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
540-38-5(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-iodo-(540-38-5)
EPA Substance Registry System
p-Iodophenol (540-38-5)
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Safety Information

Hazard Codes 
C,Xi,Xn
Risk Statements 
21/22-34-36/37/38-20/21/22
Safety Statements 
26-36/37/39-45-22
RIDADR 
UN 3261 8/PG 3
WGK Germany 
3
RTECS 
SL5600000
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, LACHRYMATOR
HS Code 
29081900

MSDS

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4-Iodophenol Usage And Synthesis

Chemical Properties

light brown powder

Uses

suzuki reaction

Uses

4-Iodophenol is used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients. Also it is used in the synthesis of agonists towards the est rogen β receptor.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 2, p. 355, 1943
The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x
Tetrahedron Letters, 40, p. 6051, 1999 DOI: 10.1016/S0040-4039(99)01236-8

Purification Methods

Crystallise 4-iodophenol from pet ether (b 80-100o) or distil it in vacuo. If the material has a brown or violet color, then dissolve it in CHCl3, shake it with 5% sodium thiosulfate solution until is colourless. Dry (Na2SO4), extract, evaporate and disil the residue in vacuo. [Dains & Eberly Org Synth Coll Vol II 355 1948, Beilstein 6 IV 1074.]

4-Iodophenol Preparation Products And Raw materials

Preparation Products

Raw materials

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4-IodophenolSupplierMore

Shanghai Boyle Chemical Co., Ltd.
Tel:
Email:
sales@boylechem.com
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
400-660-8290 21-61259100-
Email:
sh@meryer.com
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel:
010-88425576
Email:
sales@dhltchem.com
INTATRADE GmbH
Tel:
+49 3493/605464
Email:
sales@intatrade.de
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