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Nitrazepam Structure

Nitrazepam

Chemical Properties

Melting point 223-227?C
Boiling point 423.94°C (rough estimate)
Density  1.2309 (rough estimate)
refractive index  1.5700 (estimate)
Flash point 2℃
storage temp.  Controlled Substance, -20°C Freezer
solubility  Practically insoluble in water, slightly soluble in ethanol (96 per cent).
pka pKa 2.90 ± 0.05;10.39±0.04(H2O,t =25,I=0.015(KCl))(Approximate)
Water Solubility  3.93mg/L(25 ºC)
CAS DataBase Reference 146-22-5(CAS DataBase Reference)
NIST Chemistry Reference Nitrazepam(146-22-5)
EPA Substance Registry System 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl- (146-22-5)

Safety Information

Hazard Codes  Xn,F
Risk Statements  22-36-20/21/22-11
Safety Statements  36/37/39-36/37-16
RIDADR  3249
WGK Germany  3
RTECS  DF2450000
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 orally in rats: 825 ±80 mg/kg (Randall)

MSDS

Usage And Synthesis