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Androstenedione

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Androstenedione Basic information

Product Name:
Androstenedione
CAS:
63-05-8
MF:
C19H26O2
MW:
286.41
EINECS:
200-554-5
Mol File:
63-05-8.mol
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Androstenedione Chemical Properties

Melting point:
170-171 °C(lit.)
alpha 
D30 +199° (in chloroform)
Boiling point:
368.77°C (rough estimate)
Density 
1.0655 (rough estimate)
refractive index 
1.4709 (estimate)
Flash point:
2℃
storage temp. 
Controlled Substance, -20°C Freezer
color 
Dimorphous: Needles from acetone, or crystalsfrom hexane
Water Solubility 
57.28mg/L(25 ºC)
Merck 
13,643
InChIKey
AEMFNILZOJDQLW-QAGGRKNESA-N
CAS DataBase Reference
63-05-8(CAS DataBase Reference)
NIST Chemistry Reference
Androst-4-ene-3,17-dione(63-05-8)
EPA Substance Registry System
4-Androstenedione (63-05-8)
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Safety Information

Hazard Codes 
Xn,T,F
Risk Statements 
40-64-52-22-61-60-36-20/21/22-11
Safety Statements 
22-24/25-36-45-36/37-53-26-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
BV8150000
HS Code 
29372900
Hazardous Substances Data
63-05-8(Hazardous Substances Data)

MSDS

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Androstenedione Usage And Synthesis

Biological Metabolism

The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.

Chemical Properties

White to Off-White Solid

Uses

Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)

Definition

ChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.

Purification Methods

Crystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]

Androstenedione Preparation Products And Raw materials

Preparation Products

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AndrostenedioneSupplierMore

Shandong XiYa Chemical Industry Co., Ltd Gold
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3229735657@qq.com
Chembest Research Laboratories Limited
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021-20908456-
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BeiJing Hwrk Chemicals Limted
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010-57411839-
Email:
bjsales@hwrkchemical.com
Adamas Reagent, Ltd.
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400-600-9262
Email:
bxy@titansci.com
Wuhan Wei Shunda Technology Development Co., Ltd.
Tel:
86-027-88774375
Email:
mwmwhot@163.com
Basic information Biological Metabolism Safety Related Supplier