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Vitamin E succinate

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Vitamin E succinate Basic information

Product Name:
Vitamin E succinate
CAS:
4345-03-3
MF:
C33H54O5
MW:
530.78
EINECS:
224-403-8
Mol File:
4345-03-3.mol
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Vitamin E succinate Chemical Properties

Melting point:
~76 °C(lit.)
Boiling point:
625.8±55.0 °C(Predicted)
Density 
1.002±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.
form 
neat
pka
4.35±0.17(Predicted)
λmax
286nm(EtOH)(lit.)
Merck 
14,9495
BRN 
4038233
CAS DataBase Reference
4345-03-3(CAS DataBase Reference)
EPA Substance Registry System
D-.alpha.-Tocopheryl acid succinate (4345-03-3)
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Safety Information

WGK Germany 
1
RTECS 
EJ9984000
8-10-23
HS Code 
2936280000
Toxicity
LD50 oral in rat: > 7gm/kg

MSDS

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Vitamin E succinate Usage And Synthesis

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A potent antioxidant tocopherol

Uses

A potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors. Furthermore, it has been shown to enhance the anti-tumor effect of dendritic cell vaccines.

General Description

White powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Vitamin E succinate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for Vitamin E succinate are not available; however, Vitamin E succinate is probably combustible.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

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Vitamin E succinateSupplierMore

J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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jkinfo@jkchemical.com;market6@jkchemical.com
future industrial shanghai co., ltd
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400-0066-400;021-60496031
Email:
sales@jonln.com;sales@jonln.com
Arden pharmaceutical &chemical Co., Ltd
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+86-(0)533-3595900 13793319233
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info@chems.com.cn
TCI (Shanghai) Development Co., Ltd.
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021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
BeiJing Hwrk Chemicals Limted
Tel:
010-57411839-
Email:
bjsales@hwrkchemical.com
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