Propiophenone Chemical Properties
- Melting point:
- 17-19 °C(lit.)
- Boiling point:
- 218 °C(lit.)
- 1.009 g/mL at 25 °C(lit.)
- vapor pressure
- 1 mm Hg ( 50 °C)
- refractive index
- 3469 | PROPIOPHENONE
- Flash point:
- 190 °F
- storage temp.
- Store below +30°C.
- Difficult to mix.
- Clear colorless to light yellow
- Water Solubility
- JECFA Number
- Stable. Incompatible with strong oxidizing agents, strong bases.
- CAS DataBase Reference
- 93-55-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 1-Propanone, 1-phenyl-(93-55-0)
- EPA Substance Registry System
- Propiophenone (93-55-0)
Propiophenone Usage And Synthesis
Propiophenone belongs to the family of acetophenones, which is present in some certain cheese, coffee and coffee products, tea and roasted nuts with sweet-smelling odor. It is wisely used as an intermediate in the preparation of other organic compounds, such as synthetic aryl alkenes, like cinnamic acids. It is also a useful intermediate for pharmaceuticals production, such as ephedrine, propiophenone derivatives (cathinone and methcathinone), and especially for the preparation of nervous system drugs (anxiolytic and hypnotic drugs). Besides, due to its naturally pleasant flowery odor, propiophenone can be used as a component in some perfumes.
Propiophenone has a strong, flowery odor.
colourless to light yellow liquid
Reported found in coffee, roasted filberts, roasted peanuts and roasted green tea. Also reported found in Camembert cheese, black tea, roasted macadamia nut, tamarind, dried bonito, cherimoya and sapodilla fruit.
Propiophenone is an aryl ketone used in the preparation of pharmaceutical and organic compounds. Propiophenone is used in perfumes as well as in the preparation of neurochemical compounds such as ephe drines.
In perfumery; in the synthesis of ephedrine and related Compounds.
Intermediates of Liquid Crystals
ChEBI: An aromatic ketone in which the two substituents on the carbonyl C atom are phenyl and ethyl.
Propiophenone is produced by the Friedel–Crafts acylation of benzene with propionic acid chloride in the presence of aluminum chloride. It may also be produced by the reaction of benzoic acid and propionic acid using a calcium acetate– aluminum oxide catalyst.
Poison by intraperitoneal route. Moderately toxic by subcutaneous route. Mildly toxic by ingestion and skin contact. A skin and eye irritant. A flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.
Propiophenone Preparation Products And Raw materials
- 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
- METHYL 4-FLUOROBENZOYLACETATE
- Ethyl acetate
- Ethyl acrylate
- Diethyl ether
- PHENYL VALERATE
- Citric acid monohydrate