1,1,2-Trichlorotrifluoroethane Chemical Properties
- Melting point:
- −35 °C(lit.)
- Boiling point:
- 47-48 °C(lit.)
- 1.57 g/mL at 25 °C(lit.)
- vapor density
- 6.5 (vs air)
- vapor pressure
- 5.5 psi ( 20 °C)
- refractive index
- Flash point:
- storage temp.
- Water Solubility
- 0.02 g/100 mL. Slightly soluble
- Henry's Law Constant
- 0.154, 0.215, 0.245, 0.319, and 0.321 at 10, 15, 20, 25, and 30 °C, respectively (EPICS, Ashworth et al., 1988)
- Exposure limits
- TLV-TWA 1000 ppm (～7600 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 1250 ppm (ACGIH).
- Stable. Non-flammable. Incompatible with alkali metals, chemically active metals, magnesium, zinc, aluminium.
- CAS DataBase Reference
- 76-13-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethane, 1,1,2-trichloro-1,2,2-trifluoro-(76-13-1)
- EPA Substance Registry System
- CFC-113 (76-13-1)
- Hazard Codes
- Risk Statements
- Safety Statements
- UN 3082 9/PG 3
- WGK Germany
- Autoignition Temperature
- 1256 °F
- Hazard Note
- Hazardous Substances Data
- 76-13-1(Hazardous Substances Data)
- Acute oral LD50 for rats 43 mg/kg (quoted, RTECS, 1985).
1,1,2-Trichlorotrifluoroethane Usage And Synthesis
colourless liquid or gas
TTE is a colorless liquid. Carbon tetrachloride-like odor at high concentrations. A gas above 48℃.
Clear, colorless liquid with a carbon tetrachloride-like odor at high concentrations
1,1,2-Trichloro-1,2,2-trifluoroethane is usedas a refrigerant and as a drycleaning solvent.It is also used as an extraction solvent foranalyzing petroleum hydrocarbons, oils, andgreases.
Dry-cleaning solvent, fire extinguishers, to make chlorotrifluoroethylene, blowing agent, polymer intermediate, solvent drying, drying electronic parts and precision equipment.
Colorless liquid with a sweet, ether-like odor. Sinks in water.
Air & Water Reactions
Insoluble in water.
1,1,2-Trichlorotrifluoroethane yields violent reactions with Al, Ba, Li, Sm, Na/K alloy and Ti . May react exothermically with aluminum.
Inhalation causes irritation of the nose, throat, and lungs. High concentrations may cause death by respiratory failure or asphyxiation. May produce superficial skin burns or defatting type dermatitis and may irritate the eyes.
The acute oral toxicity of this compoundis very low. The oral LD50 value in ratsis 43,000 mg/kg. The inhalation toxicity isalso low. Exposure to high concentrationscan produce a weak narcotic effect, car diac sensitization, and irritation of respi ratory passage. Chronic exposure causedliver enlargement in rats. A 6-hour expo sure to 87,000 ppm of 1,1,2-trichloro-1,2,2-trifluoroethane was lethal to rats. Ingestionof the liquid may cause nausea, lethargy,nervousness, and tremor. The irritant actionof the liquid was mild on rabbits’ skin.
1,1,2-Trichlorotrifluoroethane (CFC 113) is generally a stable molecule not prone to the reactivity that is often shown by the chlorinated hydrocarbons. The solvent blends that contain the fluorinated hydrocarbon and an alcohol display some metal reactivity which is inhibited by adding nitromethane as a stabilizer.
Mildly toxic by ingestion and inhalation. Affects the central nervous system in humans. A sktn irritant. Combustible when exposed to heat or flame. Incompatible with Al, Ba, Li, Sm, NaK alloy, Ti. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and FLUORIDES.
TTE is used as a solvent and refrigerant; it is used in fire extinguishers; as a blowing agent and as an intermediate in the production of chlorotrifluoroethylene monomer by reaction with zinc.
A 2 year inhalation toxicity
study/carcinogenicity study was conducted by Trochimowicz
et al. in which groups of 100 male and 100 female
rats were exposed to levels of up to of 20,000 ppm of CFC
113 6 h/day, 5 days/week for 2 years. Although five nasal
tumors were seen, one at 20,000 ppm and four at 10,000 ppm,
all five were different morphological types and were judged
not to be exposure related. In addition, there was a small
increase (5.8%) in pancreatic islet cell adenomas in the
females exposed to 20,000 ppm; however, this was within
the normal control range.
In a second study, injection of 0.1mLof 10% CFC 113 was not carcinogenic. But when given with a 5% solution of piperonyl butoxide, hepatomas were induced in male mice. The significance of this experimental finding has never been determined.
Biological. In an anoxic aquifer beneath a landfill in Ottawa, Ontario, Canada, there was
evidence to suggest that 1,1,2-trichlorotrifluoroethane underwent reductive dehalogenation to give
1,2-difluoro-1,1,2-trichloroethylene and 1,2-dichloro-1,1,2-trifluoroethane. It was proposed that
the latter compound was degraded via dehydrodehalogenation to give 1-chloro-1,1,2-trifluoroethylene
(Lesage et al., 1990).
Chemical/Physical. 1,1,2-Trichlorotrifluoroethane will not hydrolyze to any reasonable extent (Kollig, 1993).
UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
Wash it with water, then with weak alkali. Dry it with CaCl2 or H2SO4 and distil it. [Locke et al. J Am Chem Soc 56 1726 1934, Beilstein 1 III 157, 1 IV 142.]
Violent reaction with chemically active metals (such as powdered aluminum; beryllium, magnesium and zinc); calcium. Contact with alloys containing more than 2% magnesium causes decomposition, releasing hydrogen chloride, hydrogen fluoride; and carbon monoxide. May react exothermically with aluminum.
Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced.
1,1,2-Trichlorotrifluoroethane Preparation Products And Raw materials
- 1,1-Dichloro-1-fluoroethane (Freon #141B)
- Freon R-31
- Dichlorofluoromethane (Freon #21)
- 1-Chloro-1,1-difluoroethane (Freon #142b)
- Chlorodifluoromethane (Freon #22)