尼多克罗
尼多克罗 性质
| 熔点 | 298-300° (dec) |
|---|---|
| 沸点 | 645.5±55.0 °C(Predicted) |
| 密度 | 1.472±0.06 g/cm3(Predicted) |
| 储存条件 | Sealed in dry,2-8°C |
| 溶解度 | DMSO：可溶，2mg/mL，澄清（加热） |
| 酸度系数(pKa) | 2.19±0.40(Predicted) |
| 颜色 | 白色至米色 |
尼多克罗 用途与合成方法
|
LTC 4
|
PGD 2
|
Histamine
|
Nedocromil inhibits the release of histamine, LTC 4 , and PGD 2 from mast cells challenged with antigen (with IC 30 values of 2.1 μM, 2.3 μM, and 1.9 μM, respectively) and with anti-human IgE (IC 30 values of 4.7 μM, 1.3 μM, and 1.3 μM, respectively).
Nedocromil-treated diabetic mice show significantly improved heart function compared with controls. The contractility and relaxation forces show similar improvements. However, the cardiac function of Nedocromil-treated diabetic mice remains significantly impaired when compared with normal mice. Nedocromil can significantly improve cardiac function in mice with diabetic cardiomyopathy, but the treatment cannot restore normal function.
奈多罗米二钠盐(奈多罗米钠，Nedocromil Disodium)：C19H15NO7Na2。[69049-74-7]。淡黄色结晶性粉末。
尼多克罗 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-01-25 | HY-13448 | 尼多克罗 | 69049-73-6 | 5mg | 800 |
| 2024-01-25 | HY-13448 | 尼多克罗 | 69049-73-6 | 10mM * 1mLin DMSO | 880 |
