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Salinomycin

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Salinomycin Basic information

Product Name:
Salinomycin
CAS:
53003-10-4
MF:
C42H69NaO11
MW:
772.98
EINECS:
258-290-1
Mol File:
53003-10-4.mol
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Salinomycin Chemical Properties

Melting point:
112.5-113.5 °C(lit.)
alpha 
D25 -63° (c = 1 in ethanol)
Boiling point:
839.2±65.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
Flash point:
>110°(230°F)
storage temp. 
2-8°C
form 
White solid
pka
6.4 (DMF)
Water Solubility 
Soluble in methanol. Insoluble in water
Merck 
13,8415
Stability:
Stable, but may be heat sensitive - keep cool. Incompatible with strong oxidizing agents.
CAS DataBase Reference
53003-10-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
25-36/37/38
Safety Statements 
45-36-26
RIDADR 
UN 3462 6.1/PG 2
WGK Germany 
3
RTECS 
VO8620000
10
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
53003-10-4(Hazardous Substances Data)
Toxicity
LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki)
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Salinomycin Usage And Synthesis

Chemical Properties

solid

Uses

antibacterial

Uses

Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used to control coccidia in animals and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is >100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active.

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SalinomycinSupplierMore

Guangzhou Tomums Life Science Co., Ltd Gold
Tel:
020-31155029
Email:
sales@tomums.cn
Hubei YuanCheng Pharmaceutical Co., Ltd.
Tel:
18062666904
Email:
wyy01@ycphar.com
BOC Sciences
Tel:
16316197922
Email:
info@bocsci.com
Dalian Meilun Biotech Co., Ltd.
Tel:
0411-66771943-
Email:
sales@meilune.com;sales@meilune.com;
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel:
18165736994
Email:
marketing@phystandard.com
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