Vanoxerine dihydrochloride

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Product Name:

Vanoxerine dihydrochloride

Synonyms:

Vanoxerine;GBR129092HCl;vanoxerine-GBR-12909;VANOXERINE DIHYDROCHLORIDE;1-(3-Phenylpropyl)-4-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazine;1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;GBR 12909;GBR 12909 DIHYDROCHLORIDE

CAS:

67469-78-7

MF:

C28H34Cl2F2N2O

MW:

523.49

EINECS:

Product Categories:

Dopamine receptor;TCI-

Mol File:

67469-78-7.mol

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Vanoxerine dihydrochloride Chemical Properties

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storage temp.

Desiccate at RT

solubility

DMSO: >5 mg/mL Solutions freshly prepared daily

form

solid

color

white

Water Solubility

Soluble in DMSO to 50mM. Soluble to 5mM in water with warming.

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Vanoxerine dihydrochloride Usage And Synthesis

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Uses

Antidepressant;Dopamine reuptake inhibitor

Hazard

A poison.

Biological Activity

Potent, competitive inhibitor of dopamine uptake (K i = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC 50 = 48 nM). Centrally active following systemic administration.

Product Name	Vanoxerine dihydrochloride
CAS No	67469-78-7
EC-No
Min. Order	1g
Purity	99.99%
Supply Ability	2tons
Release date	2019/12/20

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