Manufacturer Provide CAS60-80-0 Antipyrine with Safe and Fast Delivery
Introduction
1.Product Name:Antipyrine
2.Synonym:1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone
3.CAS NO: 60-80-0
4.Purity: 99%min
5.Appearance:White Crystalline Powder
6.Molecular formula: C11H12N2O
7.Molecular weight :188.23
8.Melting Point :109-111 °C(lit.)
9.Storage Temperature :Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
10.Packing: Bag, drum
Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.
Phenazone, also known as phenazon, antipyrine, or analgesine, is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. It was first synthesized by Ludwig Knorr in 1883. It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone has an elimination half life of about 12 hours.
| Item | Standard | Result |
| Appearance | White or primrose yellow crystalline powder | White crystalline powder |
| Identification | IR | Conform |
| Melting point | 109~113°C | 111.5°C |
| Appearance of Solution | clear and colorless | Conform |
| Acidity or alkalinity | complies | Conform |
| Chloride | 100ppm max | 80ppm |
| Loss on drying | ≤1.0% | 0.01% |
| Residue no Ignition | ≤0.1% | 0.04% |
| Heavy Metals | ≤0.002% | <0.002% |
| Related compounds | Meets the requirements | Conform |
| Assay (on drying) | 99.0~101% | 99.5% |
| Residual solvents(ethanol) | 1000ppm max | 275ppm |
| Related substances | impurity A | not detected |
| unspecified impurity0.05%max | not detected |
| total impurities0.1%max | not detected |
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