Ganciclovir NEW

Specification of Analysis

Description:

Ganciclovir is a parenterally-active antiviral agent indicated for sight- or life-threatening cytomegalovirus (CMV) infections in immunocompromised patients. Its suppressive effects on bone marrow and renal tubular secretion/absorption are reported to present potential limitations on adjunct therapies involving zidovudine, vincristine, adriamycin and amphotericin B. Recently, the emergence of CMV strains resistant to ganciclovir therapy has been reported.

Application:

1) Sight-threatening CMV retinitis in severely immunocompromised people
2) CMV pneumonitis in bone marrow transplant recipients
3) Prevention of CMV disease in bone marrow and solid organ transplant recipients
4) Confirmed CMV retinitis in people with AIDS (intravitreal implant)
5) It is also used for acute CMV colitis in HIV/AIDS and CMV pneumonitis in immunosuppressed patients