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Robenidine hydrochloride

$ 34.00 /1kg

Min. Order1kg
Purity99%
Cas No25875-50-7
Supply Ability1000kg
Update time2022-12-26

Hebei Duling International Trade Co. LTD

Hebei Duling International Trade Co. LTD

2YR

China

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Chemical Properties

Product Name	Robenidine hydrochloride
CAS No	25875-50-7
EC-No	247-307-8
Min. Order	1kg
Purity	99%
Supply Ability	1000kg
Release date	2022/12/26

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Email: sales02@hbduling.cn

Product Name:	Robenidine hydrochloride
Synonyms:	Robenidine hydrochloride;Robenidine HCL Pure;1,3-Bis(4-chlorobenzylideneaMino)guanidine Hydrochloride;2,2'-Bis[(4-chlorophenyl)Methylene]carboniMidic Dihydrazide Hydrochloride;ChiMcoccid Hydrochloride;KhiMcoccid Hydrochloride;Robenidine hyd;Robenidine Hydrochoride
CAS:	25875-50-7
MF:	C15H14Cl3N5
MW:	370.66
EINECS:	247-307-8
Product Categories:	Pharmaceutical intermediate;API;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors
Mol File:	25875-50-7.mol

Description	Robenidine hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an antibiotic used as an effective anticoccidial. It does not affect the earliest stages in the coccidial life-cycle and its main activity is against the almost mature first generation schizont. It is used as an aid in the prevention of coccidiosis caused by Eimeria mivati, E. brunetti, E. tenella, E. acervulina, E. maxima and E. necatrix in broiler chickens.
Chemical Properties	white or slightly yellow crystalline powder, odorless, slightly bitter taste. Very slightly soluble in ether and water, easily soluble in dilute acid or dilute alkali solution, the color gradually darkens when exposed to light.
Uses	Robenidine hydrochloride is used as a coccidiostat for use in chickens for fattening and turkeys at a minimum-maximum concentration of 30-36 mg/kg complete feed, and in rabbits for fattening at a minimummaximum concentration of 50-66 mg/kg complete feed withdrawal period of 5 days for all target animals.
Preparation	thiosemicarbazide was formed by addition and rearrangement of sodium thiocyanate with water and hydrazine. Then methylation with dimethyl sulfate and hydrazinolysis to give N.N'-diaminoguanidine sulfate. Then replaced with calcium chloride to N.N'-diaminoguanidine hydrochloride. Finally, it was condensed with p-chlorobenzaldehyde in ethanol again to produce Robenidine hydrochloride with 94% yield.

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