Cy7.5-酰肼

Cyanine7.5 hydrazide,Cy7.5 hydrazide

Cy7.5-hydrazide,Cy7.5-HZ,Cy7.5-酰肼,Cyanine7.5-hydrazide,Cyanine7.5-HZ,Cyanine7.5-酰肼

A carbonyl-reactive hydrazide derivative of Cyanine7.5 near infrared (NIR) fluorophore. This dye has similar spectral properties with ICG (indocyanine green), but has a higher quantum yield of fluorescence. Hence, this fluorophore is ideal for in vivo imaging.

This is a carbonyl-reactive dye which is particularly useful for the labeling of antibodies after periodate oxidation. It also labels other carbonyl compounds (aldehydes and ketones), for example, many saccharides.

General properties

Appearance:green powder

Mass spec M+ increment:644.4

Molecular weight:735.82

Molecular formula:C45H52Cl2N4O

Solubility:moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:NMR 1H, HPLC-MS (95%)

Storage conditions:Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm:788

ε, L⋅mol−1⋅cm−1:223000

Emission maximum, nm:808

Fluorescence quantum yield:0.10

Cyanine7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。这种染料具有与 ICG(吲哚菁绿)相似的光谱特性，但具有更高的荧光量子产率。因此，这种荧光团是体内成像的选择。

这是一种羰基反应性染料，特别适用于高碘酸氧化后的抗体标记。它还标记其他羰基化合物(醛和酮)，例如许多糖类。

一般属性

外观：绿色粉末

质谱 M+ 增量：644.4

分子量：735.82

分子式：C45H52Cl2N4O

溶解性：在水中溶解度适中，在极性有机溶剂(DMF、DMSO、醇类)中表现好

质量控制：NMR 1H、HPLC-MS (95%)

储存条件：储存：-20°C 避光保存 24 个月。运输：在室温下长达 3 周。避免长时间暴露在光线下。干燥。

光谱特性

激发/吸收，nm:788

ε, L⋅mol−1⋅cm−1:223000

发射值，nm：808

荧光量子产率：0.10

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本文由QiyueLh整理，2022年5月20日