aladdin 阿拉丁 M129245 咪唑司汀 108612-45-9 ≥98%

中文名：咪唑司汀

英文名：Mizolastine

中文别名：咪唑司汀

英文别名：GTPL10102|MLS006010068|NCGC00181013-01|AB01566892_01|Mizolastine|MIZOLASTINE [MI]|MKC431|MKC-431|Mizolastine [INN]|DTXSID5046801|Mizolastine (JAN/INN)|Tox21_112663|J-507624|T71584|Zolim|CS-1997|2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methy

纯度：≥98%

货号：M129245

包装：5g、1g

Cas号：108612-45-9

存储温度：-20°C储存

产品介绍：

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Target: Histamine H1-receptor Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat. Mizolastine has demonstrated antiallergic effects in animals and healthy volunteers and anti-inflammatory activity in animal models. Double-blind trials have shown mizolastine to be significantly more effective than placebo and as effective as other second generation antihistamine agents, such as loratadine or cetirizine, in the management of patients with perennial or seasonal allergic rhinitis and in patients with chronic idiopathic urticaria. Available data also sμggest that prophylactic administration of mizolastine is significantly more effective than placebo and as effective as prophylactic terfenadine in delaying the onset of symptoms of seasonal allergic rhinitis.Mizolastine是组胺H1受体拮抗剂，IC50为47 nM。

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