526-31-8
基本信息
ABRINE
ABRINE, L-
H-METRP-OH
L-ABRINE
N ALPHA-METHYL-L(+)-TRYPTOPHAN
N-ALPHA-METHYL-L-TRYPTOPHAN
N-A-METHYL-L-TRYPTOPHAN
N-METHYL-L-TRYPTOPHAN
N-METHYL-L-TRYPTOPHANE HYDROCHLORIDE
N-METHYLTRYPTOPHAN
N-ME-TRP-OH
N-ME-TRP-OH HCL
N-ME-TRYPTOPHAN
N-alpha-Methyl-L-trytophan
(2S)-2-(Methylamino)-3-(1H-indole-3-yl)propanoic acid
(S)-3-(1H-Indol-3-yl)-2-(methylamino)propionic acid
物理化学性质
| 熔点 | >300 °C (dec.)(lit.) |
| 比旋光度 | D21 +44° (0.28 g in 10 ml 0.5N HCl) |
| 沸点 | 358.94°C (rough estimate) |
| 密度 | 1.272±0.06 g/cm3 (20 ºC 760 Torr) |
| 折射率 | 65 ° (C=1, 0.5mol/L NaOH) |
| 储存条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
| 溶解度 | H2O : 2 mg/mL (9.16 mM; ultrasonic and adjust pH to 10 with NaOH) |
| 酸度系数(pKa) | 2.32±0.10(Predicted) |
| 形态 | Cryst. |
| 旋光性 (optical activity) | [α]20/D +65°, c = 1 in 0.5 M NaOH |
| Merck | 10 |
| BRN | 86638 |
| CAS 数据库 | 526-31-8(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H302+H312+H332 |
| 防范说明 | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 |
| 危险品标志 | Xn |
| 危险类别码 | R20/21/22 |
| 安全说明 | S36 |
| WGK Germany | 3 |
| 海关编码 | 29339900 |
应用领域
知名试剂公司产品信息
N-Methyl-L-tryptophan, 99%(526-31-8) Acros Organics
L-Abrine,>98.0%(LC)(T)(526-31-8) TCI Shanghai
相思豆毒素价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | S5828 | 相思豆毒素 L-Abrine | 526-31-8 | 25mg | 1204.73元 |
| 2018/06/12 | A1489 | L-红豆碱 L-Abrine | 526-31-8 | 200MG | 375元 |
| 2018/06/12 | A1489 | L-红豆碱 L-Abrine | 526-31-8 | 1G | 1120元 |
常见问题列表
L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine.
Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD 50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD 50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment.