LAURIFOLINE

Description

A quaternary base present in Cocculus laurifolius, the alkaloid has been isolated as the crystalline chloride, m.p. 253°C (dec.); [α]²⁴_D + 26.3° (H20). The iodide has also been prepared, this salt having an ultraviolet spectrum containing absorption maxima at 227,281 and 307 mJ1. The (±)-form of the alkaloid yields a crystalline chloride, m.p. 238°C (dec.). The base contains two methoxyl two hydroxyl and one dimethylimino group in the molecule.

target

NF-kB | Adrenergic Receptor | MAPK | HBV

References

Tomita, Kusuda., Chem. Pharm. Bull., (Tokyo), 1, 1, 5 (1953)
Albonico, Kuck, Deulofeu., Chem. Ind., 1580 (1964)
Albonico et aI., J. Chem. Soc., C, 1340 (1966)