ribavirin 5'-triphosphate

Chemical Properties

White Solid

Uses

Ribavirin Triphosphate, is a metabolite of Ribavirin (R414475), a urine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.

Uses

A metabolite of Ribavirin.

Definition

ChEBI: Ribavirin 5'-triphosphate is a 1-ribosyltriazole that is ribavirin in which the hydroxy group at the 5'-position is replaced by a triphosphate group. It is the active metabolite of the antiviral agent ribavirin. It has a role as a human blood serum metabolite, a drug metabolite, an antiviral agent, a eukaryotic initiation factor 4F inhibitor and an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor. It is a 1-ribosyltriazole, an aromatic amide, a monocarboxylic acid amide, a primary carboxamide and a ribose triphosphate. It is functionally related to a ribavirin. It is a conjugate acid of a ribavirin 5'-triphosphate(4-).