(S)-(-)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DM-SEGPHOS

Reaction

1. Biaryl bisphosphine ligand with narrow dihedral angle. The DM-SEGPHOS ligand, as the ruthenium complex, gives superior enantioselectivity and diastereoselectivity in the asymmetric hydrogenation of α-substituted-β-ketoesters. 
2. Copper catalyzed enantioselective [3 + 2] cycloaddition as a route to γ–amino ketones and 3-pyrrolidinones.
3. Palladium catalyzed enantioselective addition of malonates to dihydroisoquinolines.
4. Ruthenium catalyzed enantioselective synthesis of β amino acids by hydrogenation.
5. Ruthenium catalyzed asymmetric hydrogenation of 3-quinuclidinone. 
6. Diastereo- and enantioselective ruthenium-catalyzed hydrohydroxyalkylation of 2-silyl-butadienes. 

Uses

Uses