Uses
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain.
Uses
Pyrilamine is also used for allergy symptoms and rhinitis.
Definition
ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
brand name
Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel).
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1999, 1946
DOI: 10.1021/ja01214a037
General Description
Viscous brown liquid.
Air & Water Reactions
May be sensitive to light. Insoluble in water.
Reactivity Profile
PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.
Health Hazard
SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia.
Fire Hazard
Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible.
