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Mitomycin C Structure

Mitomycin C

Chemical Properties

Melting point 360 °C
Boiling point 471.14°C (rough estimate)
Density  1.2238 (rough estimate)
refractive index  1.6800 (estimate)
storage temp.  2-8°C
solubility  H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form  powder
pka pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color  blue-gray
PH pH (0.5 g/l, 25℃ : )5.0~7.0
Water Solubility  soluble
Merck  14,6215
BRN  7231816
Stability Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference 50-07-7(CAS DataBase Reference)
NCI Dictionary of Cancer Terms mitomycin
FDA UNII 50SG953SK6
NCI Drug Dictionary mitomycin
ATC code L01DC03
Proposition 65 List Mitomycin C
IARC 2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System Mitomycin C (50-07-7)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H300-H351
Precautionary statements P201-P202-P264-P270-P280-P301+P310
Hazard Codes  T,Xn,T+
Risk Statements  25-40-22-45-26/27/28
Safety Statements  36/37-45-28A-28-53-22
RIDADR  UN 3462 6.1/PG 2
WGK Germany  3
RTECS  CN0700000
8-10
TSCA  Yes
HazardClass  6.1(a)
PackingGroup  II
HS Code  29419090
Hazardous Substances Data 50-07-7(Hazardous Substances Data)
Toxicity LD50 i.v. in mice: 5 mg/kg (Wakaki); also reported as 9 mg/kg (Kinoshita)
NFPA 704:
0
4 0

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