2-Formylcyclopropane-1-carboxylic Acid Ethyl Ester acts as a reagent for the design, synthesis and biological evaluation of first-in-class dual acting histone deacetylase (HDACs) and phosphodiesterase 5 (PDE5) inhibitors for treatment of Alzheimer’s disease.
Ethyl 2-formyl-1-cyclopropanecarboxylate was used in the preparation of ethyl trans-2-(4-(methylphenyl)sulfonyl-4,5-dihydrooxazol-5-yl)cyclopropanecarboxylate.
Ethyl 2-formyl-1-cyclopropanecarboxylate was formed by acid catalyzed reaction between acrolein and ethyl diazoacetate.
