USP 99% Isosorbide Dinitrate Powder CAS 87-33-2
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Product Information
Product Description
Isosorbide Dinitrate is a moderate to long acting oral organic nitrate used for the relief and prophylactic management of angina pectoris. It relaxes the vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter. Dilatation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end- diastolic pressure and pulmonary capillary wedge pressure (preload). Arteriolar relaxation reduces systemic vascular resistance, systolic arterial pressure, and mean arterial pressure.Function
Similar to other nitrites and organic nitrates, isosorbide dinitrate is converted to nitric oxid e (NO), an active intermediate compound which activates the enzyme guanylate cyclase (atrial natriuretic peptide receptor A). This stimulates the synthesis of cyclic guanosine 3',5'-monophosphate (cGMP) which then activates a series of protein kinase-dependent phosphorylations in the smooth muscle cells, eventually resulting in the dephosphorylation of the myosin light chain of the smooth muscle fiber. The subsequent release of calcium ions results in the relaxation of the smooth muscle cells and vasodilation.
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| By Express | By Air | By Sea |
| Suitable for under 50kg | Suitable for more than 50kg | Suitable for more than 500kg |
| Fast: 3-7 days | Fast: 3-7 days | Slow: 3-10 days |
| High cost | Medium cost | Medium cost |
| Door to door service | Door to door service | Port to port service |
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FAQ:
Q1: Can I get a sample?
A:Free samples is available, while the shipping cost should undertake by your side.
Q2: What is your MOQ?
A:Our MOQ is 10g, 100g and 1kg for your evaluation quality of our goods on the condition that sample charge is 100% paid.
Q3: Is there any discount?
A:Yes, for larger quantity, we always support with better price.
Q4: What payment terms do you accept ?
A:We'd like to accept T/T, L/C, Paypal, or Western Union.
Q5: How long will it take to get the good?
A:Depending on your location, For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS. For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Why You Choose Us?
1. Rich experience
We specialize in this filed for many years,our steriods and hormones exported to all over the world and established long friendly relations of cooperation with them.
2. Great quality,purity and favorable
Good quality is one of our biggest secret to success;u can get the best quality and service from us.
3. Safest and fastest delivery
We have adequate stock so that we can deliver the products with 24 hours as soon as receiving the payment.Fast and discreet shipment will be arranged to pass customs.
4. Good package
Unique ways to ship 10g to 100kg powders to your destination.We offer melting powder into liquid service and ship the liquid in special bottles.
5. Great after-sales service
Any needs or questions contact me freely.
Don't worry about working with us:
1. If the goods are withheld by the customs and cannot be received, we have special customs clearance personnel. Generally, the goods will be delivered to the customers within the specified time, so as to avoid the influence of weather and international situation. If the goods are not received, we will refund the full amount.
2. If the goods are not delivered for a long time after payment, all kinds of goods we sell are in stock. We will communicate with customers about the delivery time or port before selling. If the goods are not delivered after the time limit, we will refund the full amount.
3. The product quality and purity are not high. Our products will have strict quality inspection before leaving the factory. If the product is wrong or the product quality is unqualified, we will return the full payment.
804
China
