Chemical Properties
Pale Yellow Solid
Originator
Arprinocid,NANJING PHARMA
Uses
Arprinocide can be used as a Coccidiostat used in veterinary medicine.
Definition
ChEBI: Arprinocid is a member of 6-aminopurines.
Manufacturing Process
To a solution of potassium t-butoxide in absolute ethanol slowly adding dry
adenine. This mixture was stirred for about 2 h, and then 2-chloro-6-
fluorobenzyl chloride was added over a period of about 4 h. The resulting
mixture was heated to reflux with stirring and allowed to react for about 42 h,
after which it was cooled to about 10°C. The crude product thus formed was
isolated by filtration and then washed with ice cold ethanol and ice cold water
to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine.
brand name
Arpocox (Merck).
Therapeutic Function
Coccidiostatic
Synthesis Reference(s)
The Journal of Organic Chemistry, 43, p. 960, 1978
DOI: 10.1021/jo00399a034
