ChemicalBook >  Product Catalog >  API >  Fluid, Electrolyte, and Acid-Base Balance >  Electrolyte Balance Pharmacology >  Calcium gluconate

Calcium gluconate

Basic information Description References Safety Related Supplier

Calcium gluconate Basic information

Product Name:
Calcium gluconate
CAS:
299-28-5
MF:
C12H22CaO14
MW:
430.37
EINECS:
206-075-8
Mol File:
299-28-5.mol
More
Less

Calcium gluconate Chemical Properties

Melting point:
195°C
alpha 
10.2 º (c=1, H2O 22 ºC)
solubility 
Sparingly soluble in water, freely soluble in boiling water.
form 
Crystals or Crystalline Powder
color 
White
PH
pH;6.0~8.0
Water Solubility 
3.3 g/100mL
Hydrolytic Sensitivity
0: forms stable aqueous solutions
Merck 
14,1669
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
KYUVBRZSDFBLTH-OSQBQZLYSA-M
CAS DataBase Reference
299-28-5(CAS DataBase Reference)
EPA Substance Registry System
D-Gluconic acid, calcium salt (2:1) (299-28-5)
More
Less

Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
1
RTECS 
EW2100000
TSCA 
No
HS Code 
29181600
Hazardous Substances Data
299-28-5(Hazardous Substances Data)

MSDS

More
Less

Calcium gluconate Usage And Synthesis

Description

Calcium gluconate is the calcium salt of gluconate, being an oxidative product of glucose containing 9.3% calcium. Calcium gluconate is a kind of mineral supplement and medication. It can be used for vein injection to treat the low blood calcium, high blood potassium, and magnesium toxicity. It is required only when there is not enough calcium in the diet. It is also used for the treatment of black widow spider bites to relieve muscle cramping and treatment of osteoporosis or rickets. It can also be used to decrease the capillary permeability in allergic conditions, nonthrombocytopenic purpura and exudative dermatoses.

References

http://www.drugbank.ca/drugs/DB11126 https://en.wikipedia.org/wiki/Calcium_gluconate

Chemical Properties

white crystalline powder or granules

Uses

analgesic, antipyretic

Uses

Calcium Gluconate is used as an inert ingredient in pesticide formulations applied to crops. It is also used as a supplement to fortify beverages and foods lacking a sufficient amount of calcium.

Uses

In sewage purification; in coffee powders to prevent caking.

Uses

Calcium Gluconate is a white crystalline granule or powder that functions as a firming agent, formulation aid, sequestrant, and sta- bilizer. at room temperature the anhydrous form has a solubility of approximately 1 g in 30 ml of water, which improves in boiling water to approximately 1 g in 5 ml of water. it also exists as calcium gluconate (monohydrate). it is used as a source of calcium ions for sodium alginate gels, and as a calcium fortifier in baked goods, pud- dings, and dairy product analogs. it functions as a coagulation aid in milk and instant pudding powders and as a means of masking the bitter aftertaste of some artificial sweeteners.

brand name

Calglucon (Novartis).

Industrial uses

calcium gluconate [Ca(C6H11O7)2] is used as a food additive in vitamin pills.injection of a 10% calcium gluconate has been recommended. It has to be kept in mind that the plasma Ca2+ level and any changes to the electrocardiogram (ECG) have to be carefully monitored.

Safety Profile

Moderately toxic by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects in infants by intramuscular route: dermatitis and fever. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS.

Veterinary Drugs and Treatments

Calcium salts are used for the prevention or treatment of hypocalcemic conditions.

Purification Methods

Dissolve it in H2O, filter and precipitate it by adding MeOH. Filter off the solid and dry it in a vacuum at 85o. Alternatively, dissolve it in H2O, filter (from insoluble inorganic Ca) and evaporate it to dryness under vacuum at 85o. [March et al. J Am Pharm Assoc 41 366 1952, Beilstein 3 IV 1255.]

More
Less

Calcium gluconateSupplierMore

J & K SCIENTIFIC LTD.
Tel:
010-82848833- ;010-82848833-
Email:
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
21-61259100-
Email:
sh@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
821-50328103-801
Email:
3bsc@sina.com
Alfa Aesar
Tel:
400-610-6006; 021-67582000
Email:
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel:
021-67121386 / 800-988-0390
Email:
Sales-CN@TCIchemicals.com
Basic information Description References Safety Related Supplier